This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by HEYDEN, S. Articles by GOREE, J. A. Search for Related Content PubMed PubMed Citation Articles by HEYDEN, S. Articles by GOREE, J. A.

(Stroke. 1970;1:363.)
© 1970 American Heart Association, Inc.

---

Nonembolic Occlusion of the Middle Cerebral and Carotid Arteries—A Comparison of Predisposing Factors

SIEGFRIED HEYDEN M.D.¹; ALBERT HEYMAN M.D.²; JOHN A. GOREE M.D.²

¹ Department of Community Health Sciences; Duke University Medical School, Durham, North Carolina, 27706
² Department of Radiology; Duke University Medical School, Durham, North Carolina, 27706

Selected clinical characteristics of patients with nonembolic occlusion of the middle cerebral artery were compared with those of patients with atherosclerotic occlusive lesions at the bifurcation of the common carotid artery. Unexpected differences were observed in the race-age distribution, in the presence of systemic vascular disease, and in the frequency of factors predisposing to atherosclerosis. The group with intracranial arterial lesions included more Negro patients than the group with lesions in the extracranial carotid artery. Ischemic heart disease, intermittent claudication and hypercholesterolemia were more frequent among the patients with extracranial cerebrovascular lesions, but the incidence of hypertension and diabetes was the same in both groups. These findings suggest differences in the etiological and pathogenetical mechanisms of the vascular disease in patients with extracranial and intracranial cerebral arterial occlusive lesions.

Key Words: carotid and coronary artery disease • predisposing factors to atherosclerosis • race differences

This article has been cited by other articles:

				A. T. Schneider, B. Kissela, D. Woo, D. Kleindorfer, K. Alwell, R. Miller, J. Szaflarski, J. Gebel, J. Khoury, R. Shukla, et al. Ischemic Stroke Subtypes: A Population-Based Study of Incidence Rates Among Blacks and Whites Stroke, July 1, 2004; 35(7): 1552 - 1556. [Abstract] [Full Text] [PDF]

				Angioplasty and Stenting of Extracranial Brachiocephalic Stenoses (Other Than the Cervical Carotid Bifurcation) and Intracranial Stenoses AJNR Am. J. Neuroradiol., September 1, 2001; 22(2007): 31S - 33S. [Full Text] [PDF]

				P. B. Gorelick Cerebrovascular Disease in African Americans Stroke, December 1, 1998; 29(12): 2656 - 2664. [Full Text] [PDF]

				R. J. Wityk, D. Lehman, M. Klag, J. Coresh, H. Ahn, and B. Litt Race and Sex Differences in the Distribution of Cerebral Atherosclerosis Stroke, November 1, 1996; 27(11): 1974 - 1980. [Abstract] [Full Text]

				R. L. Sacco, D. E. Kargman, Q. Gu, and M. C. Zamanillo Race-Ethnicity and Determinants of Intracranial Atherosclerotic Cerebral Infarction : The Northern Manhattan Stroke Study Stroke, January 1, 1995; 26(1): 14 - 20. [Abstract] [Full Text]