Stroke, Vol 10, 326-330, Copyright © 1979 by American Heart Association
MP Spencer and JM Reid
Two methods for determining the degree of stenoses developing on the origin
of the internal carotid were tested using non-invasive Doppler ultrasonic
imaging (DOPSCAN) of the carotid bifurcations. Spectral analysis of Doppler
audio recordings was utilized in determining the maximum frequencies found
within the stenosis, as well as the ratio of the frequency downstream to
the stenosis, to the frequency within the stenosis. The theoretical
relationships between blood flow, velocity, and pressure drop are defined
for all grades of stenosis and they predict that carotid flow will not be
reduced unless the lumen diameter is less than 1.5 mm. At critical diameter
reductions, below 1 mm, the frequencies in human carotids do not exceed 16
KHz because turbulence limits peak velocities. If the maximum systolic
frequency exceeds 5 KHZ, when 5 MHZ probes are directed at a 30 degree
angle from the body axis, there is always present stenosis up to diameters
of less than 3.5 mm by x-ray angiographic measurements. Frequency ratio
studies confirm that plaque growth is not symmetrical but they did not
improve x-ray angiography correlations because of the limitations of x-ray
in measuring cross sectional areas from projection films and limitations of
the spot size of x-ray tubes.
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