Stroke, Vol 11, 14-21, Copyright © 1980 by American Heart Association
A Kagan, JS Popper and GG Rhoads
As part of an ongoing longitudinal study of coronary heart disease and
stroke among Japanese men in Hawaii, 8,006 men of Japanese ancestry living
on the island of Oahu and aged 45-68 at entry examination have been
followed by reexamination and surveillance. One hundred and eleven were
found to have evidence of prior stroke at the time of the initial
examination. During a six-year follow up period of the remaining 7,895 men,
94 developed definite thromboembolic stroke, 33 definite intracranial
hemorrhage, and 6 developed stroke of unknown type. The principal risk
factors for thromboembolic stroke were: elevated blood pressure, glucose
intolerance, age, and electrocardiography evidence of left ventricular
hypertrophy or strain. Attributes associated with increased risk of
intracranial hemorrhage were elevated blood pressure, electrocardiographic
evidence of left ventricular hypertrophy or strain, and alcohol intake.
Serum cholesterol level was negatively associated with risk of intracranial
hemorrhage.
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Factors related to stroke incidence in Hawaii Japanese men. The Honolulu Heart Study
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|
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|
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|
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|
|
|
|
 |
|
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|
|
|
|
|
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|
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