This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Maximilian, V. A. Articles by Risberg, J. Search for Related Content PubMed PubMed Citation Articles by Maximilian, V. A. Articles by Risberg, J.

Stroke, Vol 11, 342-347, Copyright © 1980 by American Heart Association

ARTICLES

Cerebral hemodynamic response to mental activation in normo- and hypercapnia

VA Maximilian, I Prohovnik and J Risberg

Changes of regional cerebral blood flow from rest to mental activation by a visually presented spatial reasoning test were measured during normo- and hypercapnia in 10 healthy subjects. Hypercapnia, elicited by inhalation of 6% CO2, resulted in similar flow increases in all 32 cortical regions measured. Increases of flow during testing were seen in post-central regions of the brain whether the resting level was augmented by hypercapnia or not. The results show that an elevated local functional level in the cortex causes an automatic local vasodilatory response which is totally independent of the basal level of perfusion and availability of metabolic substrates.

This article has been cited by other articles:

				I. H. Lorenz, C. Kolbitsch, C. Hormann, T. J. Luger, M. Schocke, S. Felber, F. Zschiegner, M. Hinteregger, C. Kremser, and A. Benzer Influence of equianaesthetic concentrations of nitrous oxide and isoflurane on regional cerebral blood flow, regional cerebral blood volume, and regional mean transit time in human volunteers Br. J. Anaesth., November 1, 2001; 87(5): 691 - 698. [Abstract] [Full Text] [PDF]

				C. Kolbitsch, I. H. Lorenz, C. Hormann, M. Schocke, C. Kremser, F. Zschiegner, A. Lockinger, K. P. Pfeiffer, S. Felber, and A. Benzer A Subanesthetic Concentration of Sevoflurane Increases Regional Cerebral Blood Flow and Regional Cerebral Blood Volume and Decreases Regional Mean Transit Time and Regional Cerebrovascular Resistance in Volunteers Anesth. Analg., July 1, 2000; 91(1): 156 - 162. [Abstract] [Full Text] [PDF]