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Stroke, Vol 12, 173-176, Copyright © 1981 by American Heart Association

ARTICLES

Serial measurements of positron-emitting isotope activity in rat brain

AH Lockwood and PJ Kenny

This report describes the construction and performance characteristics of a device capable of making rapid serial measurement of rat brain radioactivity following the administration of a positron emitting isotope. Two bismuth germanate oxide (BGO) scintillation detectors in a coincidence detection circuit are used to achieve the necessary degree of collimation. Data from the device can be used to characterize cerebral biochemical and physiological processes using computer- assisted mathematical models.

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