Stroke, Vol 13, 821-824, Copyright © 1982 by American Heart Association
DJ Marzewski, AJ Furlan, P St. Louis, JR Little, MT Modic and G Williams
Sixty-six patients with greater than or equal to 50% stenosis of an
intracranial internal carotid artery (IICA) were followed-up for an average
of 3.9 years. Eighteen patients (27.3%) experienced ischemic events; 8
(12.1%) had isolated TIA and 10 (15.2%) a stroke. The observed stroke rate
for patients 35 years and older are 13 times the expected infarction rate
for a normal population. Patients with tandem extracranial stenosis had a
greater risk of stroke than patients with isolated IICA stenosis.
Thirty-three patients (50%) died during follow- up and 55% of all deaths
were cardiac related. The observed 5 year survival rate was 60% compared to
an expected rate of 87%. Patients with IICA stenosis had a higher risk of
stroke and death compared to a previously reported referral population with
ICA occlusion. IICA stenosis is a marker of extensive cerebrovascular and
systemic atherosclerotic disease, especially coronary artery disease.
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