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Stroke, Vol 14, 885-892, Copyright © 1983 by American Heart Association
PM Chikos, LD Fisher, JH Hirsch, JD Harley, BL Thiele and DE Strandness Jr
One hundred twenty eight cervical carotid arteriograms were twice viewed by
three readers for the evaluation of atherosclerotic disease at the carotid
bifurcation. Stenoses were estimated using calipers to the nearest 5% and
lesions were qualitatively characterized as smooth, irregular, or
ulcerated. The intraobserver correlation coefficient between estimates of
percent stenosis was .94 overall and .98 for the internal carotid artery.
The average intraobserver variability in estimating percent stenosis was
5.23% for all vessels and 6.04% with a standard deviation of 8.09% for the
internal carotid artery. The intraobserver percent agreement at a fixed
stenosis is defined as the percent of the time one reader on two readings
would read at least the fixed percent stenosis among cases that might be
read as having the fixed percent stenosis. The intraobserver percent
agreement rate for the internal carotid artery was 95.9% at greater than 0%
stenosis, 90.4% for 50% or greater stenosis, and 96.8% for 100% stenosis
(total occlusion). The interobserver correlation coefficient between
readers was .92 overall and .97 for the internal carotid artery. The
absolute difference in percent stenosis between readers was 7.21% for all
vessels and 8.64% for the internal carotid artery with a standard deviation
of 9.5%. The interobserver agreement rate for the internal carotid artery
at greater than 0% stenosis was 93.0%, 85.4% for 50% or greater stenosis
and 96.8% at 100% stenosis. The addition of oblique views had no
statistical effect on estimates of percent stenosis but increased the
frequency with which irregularity and ulceration were diagnosed in the
internal carotid artery.
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Observer variability in evaluating extracranial carotid artery stenosis
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