Stroke, Vol 16, 390-396, Copyright © 1985 by American Heart Association
A Kagan, JS Popper, GG Rhoads and K Yano
As part of an on-going longitudinal study, 7895 men of Japanese ancestry
living on the island of Oahu, aged 45-68 and free of evidence of prior
stroke at entry examination, have been followed by re- examinations and
surveillance. During ten years of follow-up 154 men developed
thromboembolic stroke, 65 developed intracranial hemorrhage, and 19
developed stroke of unknown type. There were 79 deaths attributed to
stroke. The independent risk factors for thrombo-embolic stroke were
elevated blood pressure, glucose intolerance, age, electrocardiographic
evidence of left ventricular hypertrophy or strain, cigarette smoking and
proteinuria. Attributes associated with increased risk of intracranial
hemorrhage were age, elevated blood pressure, cigarette smoking, serum uric
acid and, inversely, serum cholesterol level. Electrocardiographic evidence
of left ventricular hypertrophy or strain significantly increased the risk
of cerebral hemorrhage, but was not associated with subarachnoid
hemorrhage. In univariate analysis, there was an inverse relation between
dietary fat intake and thrombo-embolic and total stroke incidence. An
inverse relation was also shown between protein intake and total stroke
incidence. These dietary relations became statistically not significant in
multivariate analysis. No relation was found between salt intake and the
incidence of stroke.
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Dietary and other risk factors for stroke in Hawaiian Japanese men
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