Stroke, Vol 17, 613-616, Copyright © 1986 by American Heart Association
D Front, A Frankel, O Israel, Y Aharon, A Satinger and S Linn
The ejection fraction (EF) of the left ventricle was measured by
radionuclide ventriculography in 64 patients during an acute
cerebrovascular accident. Sixteen patients (12 with coronary artery
disease) died within two weeks of the onset of symptoms and had only one EF
measurement. In the remaining 48 patients, the EF was also measured two
weeks and three months after the acute event. The ejection fraction of the
patient who died soon after the acute stroke (52 +/- 18) was significantly
lower than that of the patients who survived (64 +/- 10) (p less than
0.01). Of the patients who survived, 28 without history of coronary disease
had an EF of 67 +/- 10 during the acute event. It was significantly higher
than that measured after two weeks (60 +/- 10) p less than 0.01). In 10
patients with history of chronic stable angina pectoris, the EF (59 +/- 10)
was significantly lower in the first study compared to that measured in the
second (69 +/- 10) (p less than 0.02). Ten patients with no evidence of
ischemia but with a history of myocardial infarction had a higher EF (61
+/- 11) during the first study as compared to the second (51 +/- 11) (p
less than 0.05). In all patients there was no significant difference in the
EF measurements between the second and the third study. It is suggested
that the EF response of the left ventricle of the heart to the acute
cerebrovascular accident is similar to that observed in a stress
test.(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Ejection fraction response of the left ventricle of the heart to acute cerebrovascular accident in patients with coronary artery disease
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