Stroke, Vol 17, 630-637, Copyright © 1986 by American Heart Association
BR Ott, A Zamani, J Kleefield and HH Funkenstein
The hospital records and head CT scans of 44 patients with hemorrhagic
infarction were retrospectively analyzed. The majority of cases (73%) were
embolic or possibly embolic in etiology, and 55% were not associated with
anticoagulant therapy. Adverse prognosis was most clearly related to
infarct size, underlying systemic illness, and symptomatic hemorrhage. Of
the nineteen patients in whom serial CT scans documented conversion from
bland to hemorrhagic infarction, 12 exhibited no clinical worsening at the
time that hemorrhagic infarction was observed; the remaining seven, all of
whom worsened, were receiving anticoagulant therapy at the time of
documented conversion. Fourteen patients in whom anticoagulant therapy was
used despite the findings of hemorrhagic infarction remained stable or
improved during hospitalization.
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