Stroke, Vol 17, 891-897, Copyright © 1986 by American Heart Association
WT Blume, GG Ferguson and DK McNeill
Visually apparent EEG changes associated with clamping the internal carotid
artery appeared in 55 of 176 consecutive patients (31%) undergoing carotid
endarterectomy without shunt. Attenuation of higher frequency activity was
the most common change. Changes were moderate in 33 patients (19%) and
major in 22 (12.5%). Major changes usually commenced earlier than less
severe alterations. EEG changes resolved within 10 minutes of clamp release
in 36 of 55 patients (65%) after an average clamp time of 36.25 minutes.
Changes occurred more commonly when pre-operative EEGs were abnormal
contralateral to clamping and when the contralateral carotid artery was
more than 90% stenosed. Of the inhalational anesthetics employed with
nitrous oxide and oxygen, isoflurane was associated with the lowest
incidence of clamp-associated EEG change. Post-operative strokes occurred
in 2 of 22 patients (9%) with major clamp-associated EEG changes, none of
33 patients with moderate changes and none of 121 without changes. However,
the mechanism of this relationship remains in doubt.
ARTICLES
Significance of EEG changes at carotid endarterectomy
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