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Stroke, Vol 17, 891-897, Copyright © 1986 by American Heart Association


ARTICLES

Significance of EEG changes at carotid endarterectomy

WT Blume, GG Ferguson and DK McNeill

Visually apparent EEG changes associated with clamping the internal carotid artery appeared in 55 of 176 consecutive patients (31%) undergoing carotid endarterectomy without shunt. Attenuation of higher frequency activity was the most common change. Changes were moderate in 33 patients (19%) and major in 22 (12.5%). Major changes usually commenced earlier than less severe alterations. EEG changes resolved within 10 minutes of clamp release in 36 of 55 patients (65%) after an average clamp time of 36.25 minutes. Changes occurred more commonly when pre-operative EEGs were abnormal contralateral to clamping and when the contralateral carotid artery was more than 90% stenosed. Of the inhalational anesthetics employed with nitrous oxide and oxygen, isoflurane was associated with the lowest incidence of clamp-associated EEG change. Post-operative strokes occurred in 2 of 22 patients (9%) with major clamp-associated EEG changes, none of 33 patients with moderate changes and none of 121 without changes. However, the mechanism of this relationship remains in doubt.


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