Stroke, Vol 17, 913-915, Copyright © 1986 by American Heart Association
CC Bishop, S Powell, D Rutt and NL Browse
Measurement of intracranial arterial blood flow velocity is a new technique
with potentially a number of very useful applications. This study validates
the technique by comparing it to cerebral blood flow (CBF) measured using
intravenous Xenon133 and extracranial clearance recording. We have measured
the middle cerebral artery (MCA) blood flow velocity in 17 symptomatic
patients with the EME TC 264 transcranial Doppler velocimeter and compared
these measurements to the ipsilateral hemispheric cerebral blood flow
measured with an intravenous Xenon133 technique (Novo Cerebrograph 10A).
Measurements were made at rest and during hypercapnia. The absolute
measurement of MCA velocity and hemispheric CBF showed a poor correlation
(r = 0.424, p less than 0.01) due to wide between-patient variations at
rest but the blood flow response to hypercapnia, expressed as a reactivity
index, showed a good correlation (r = 0.849, p less than 0.001). Thus
changes in MCA velocity reliably correlate with changes in cerebral blood
flow but the absolute velocity cannot be used as an indicator of CBF.
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Transcranial Doppler measurement of middle cerebral artery blood flow velocity: a validation study
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A. E. Jonassen, J. M.Quaegebeur, and W. L. Young CEREBRAL BLOOD FLOW VELOCITY IN PEDIATRIC PATIENTS IS REDUCED AFTER CARDIOPULMONARY BYPASS WITH PROFOUND HYPOTHERMIA J. Thorac. Cardiovasc. Surg., October 1, 1995; 110(4): 934 - 943. [Abstract] [Full Text]
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P.P. Urban, A. Allardt, B. Tettenborn, H.C. Hopf, S. Pfennigsdorf, and W. Lieb Photoreactive Flow Changes in the Posterior Cerebral Artery in Control Subjects and Patients With Occipital Lobe Infarction Stroke, October 1, 1995; 26(10): 1817 - 1819. [Abstract] [Full Text]
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W. A. Kofke, P. Brauer, R. Policare, S. Penthany, D. Barker, and J. Horton Middle Cerebral Artery Blood Flow Velocity and Stable Xenon-Enhanced Computed Tomographic Blood Flow During Balloon Test Occlusion of the Internal Carotid Artery Stroke, September 1, 1995; 26(9): 1603 - 1606. [Abstract] [Full Text]
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M. Muller, M. Voges, U. Piepgras, and K. Schimrigk Assessment of Cerebral Vasomotor Reactivity by Transcranial Doppler Ultrasound and Breath-Holding : A Comparison With Acetazolamide as Vasodilatory Stimulus Stroke, January 1, 1995; 26(1): 96 - 100. [Abstract] [Full Text]
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 A. Q. Fischer, M. A. Taormina, B. Akhtar, and B. A. Chaudhary The Effect of Sleep on Intracranial Hemodynamics: A Transcranial Doppler Study J Child Neurol, April 1, 1991; 6(2): 155 - 158. [Abstract] [PDF]
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 R. E. Kelley, R. A. Namon, Shing-Her-Juang, S.-C. Lee, and J. Y. Chang Transcranial Doppler Ultrasonography of the Middle Cerebral Artery in the Hemodynamic Assessment of Internal Carotid Artery Stenosis Arch Neurol, September 1, 1990; 47(9): 960 - 964. [Abstract] [PDF]
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A. Q. Fischer and J. N. Livingstone Transcranial Doppler and Real-Time Cranial Sonography in Neonatal Hydrocephalus J Child Neurol, January 1, 1989; 4(1): 64 - 69. [Abstract] [PDF]
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