Stroke, Vol 17, 1098-1101, Copyright © 1986 by American Heart Association
G Di Pasquale, A Andreoli, G Pinelli, P Grazi, G Manini, F Tognetti and C Testa
A prospective cardiologic evaluation was performed in 83 consecutive
patients with transient cerebral ischemia or mild stroke and without
symptoms or electrocardiographic signs of ischemic heart disease. Patients
were studied with an electrocardiographic exercise test; a positive test
was followed by exercise Thallium-201 myocardial scintigraphy. Results were
compared to those obtained in a group of 83 age and sex-matched healthy
subjects submitted to the same study protocol. Asymptomatic coronary artery
disease was detected in 28% of cerebrovascular patients with adequate
electrocardiographic exercise test. A scintigraphic perfusion defect of
variable extension was found in 19 of them. In the control group the
electrocardiographic exercise test was positive in only 6% (p less than
0.01). Our results support the concept that: asymptomatic ischemic heart
disease is often associated with cerebrovascular disease; therefore
cerebral ischemic attacks may be a marker of coronary artery disease, an
active investigation of the heart should be considered in cerebrovascular
patients in order to plan optimal, comprehensive management.
ARTICLES
Cerebral ischemia and asymptomatic coronary artery disease: a prospective study of 83 patients
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