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Stroke, Vol 18, 524-527, Copyright © 1987 by American Heart Association

ARTICLES

Acute stroke therapy trials: an introduction to recurring design issues

AB Sterman, AJ Furlan, M Pessin, C Kase, L Caplan and G Williams

We discuss selected issues concerning the design of stroke treatment trials. Key issues include the type of stroke studied, the time interval from stroke onset to patient entry, and whether to include cardioembolic strokes and allow concomitant therapy.

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