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Stroke, Vol 18, 801-804, Copyright © 1987 by American Heart Association

ARTICLES

Cerebral venous thrombosis with lupus anticoagulants. Report of two cases

SR Levine, S Kieran, K Puzio, H Feit, SC Patel and KM Welch

Lupus anticoagulants are circulating autoantibodies, primarily directed against phospholipids, that prolong the partial thromboplastin time. They have been previously associated with systemic arterial and venous thrombosis and arterial stroke, but not with cerebral venous thrombosis. We describe 2 young patients with cerebral venous thrombosis documented by intravenous digital subtraction angiography in whom a lupus anticoagulant was demonstrated. Both patients improved with corticosteroid and anticoagulant therapy.

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