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Stroke, Vol 18, 1101-1106, Copyright © 1987 by American Heart Association

ARTICLES

Ischemic stroke associated with anticardiolipin antibodies

SR Levine, S Kim, MJ Deegan and KM Welch
Department of Neurology, Henry Ford Hospital, Detroit, MI 48202.

Anticardiolipin antibodies are a group of antiphospholipid autoantibodies seen primarily in patients with systemic lupus erythematosus and other autoimmune diseases. We report 3 patients, 2 without systemic lupus, who suffered ischemic brain infarction associated with these antibodies in the absence of detectable lupus anticoagulant activity. Anticardiolipin antibodies, possibly associated with a lupus anticoagulant-like thrombotic tendency, may be a newly recognized cause of ischemic stroke.

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