Stroke, Vol 19, 1435-1440, Copyright © 1988 by American Heart Association
LE Knepper, J Biller, HP Adams Jr and A Bruno
We present the results of a 12-year retrospective analysis of 11 patients,
eight women and three men, aged 16-76 years, with pathologically documented
atrial myxomas. Nine of the 11 patients were found to have a left atrial
myxoma; right atrial myxomas were identified in two. Five of the 11
patients (45%) had abnormalities on neurologic examination, and five of
five had computed tomographic evidence of nonhemorrhagic cerebral
infarction. Neurologic symptoms were the initial presentation in four
patients. Six patients reported a history of cardiac disease; eight of the
11 had abnormalities on cardiac auscultation. Echocardiography in 10
patients was diagnostic in all but one. Gated magnetic resonance imaging of
the heart in two patients demonstrated myxoma position and movement.
Follow-up examinations (varying from 1 month to 7 years after tumor
resection) in nine of 11 patients demonstrated no recurrent neurologic
symptoms. Cerebral infarction is a common complication of atrial myxomas
and may be the presenting feature. Recurrent cerebral emboli before surgery
is not uncommon. Cardiac auscultation may be normal, and
electrocardiographic changes are often nonspecific. Delayed neurologic
events following surgery are rare.
ARTICLES
Neurologic manifestations of atrial myxoma. A 12-year experience and review
Department of Neurology, University of Iowa College of Medicine, Iowa City 52242.
This article has been cited by other articles:
 |
|
 |
|
  A. W. ElBardissi, J. A. Dearani, R. C. Daly, C. J. Mullany, T. A. Orszulak, F. J. Puga, and H. V. Schaff Embolic Potential of Cardiac Tumors and Outcome After Resection: A Case-Control Study Stroke, January 1, 2009; 40(1): 156 - 162. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. B. Rahmanian, J. G. Castillo, J. Sanz, D. H. Adams, and F. Filsoufi Cardiac myxoma: preoperative diagnosis using a multimodal imaging approach and surgical outcome in a large contemporary series Interactive CardioVascular and Thoracic Surgery, August 1, 2007; 6(4): 479 - 483. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. H. Lee, H. M. Connolly, and R. D. Brown Jr Central Nervous System Manifestations of Cardiac Myxoma Arch Neurol, August 1, 2007; 64(8): 1115 - 1120. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Herbst, M. P. Wattjes, H. Urbach, C. Inhetvin-Hutter, D. Becker, T. Klockgether, and A. Hartmann Cerebral Embolism from Left Atrial Myxoma Leading to Cerebral and Retinal Aneurysms: A Case Report AJNR Am. J. Neuroradiol., March 1, 2005; 26(3): 666 - 669. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. O'Rourke, N. Dean, M. S. Mouradian, N. Akhtar, and A. Shuaib Atrial myxoma as a cause of stroke: case report and discussion Can. Med. Assoc. J., November 11, 2003; 169(10): 1049 - 1051. [Abstract] [Full Text]
|
|
|
|
 |
|
 M. Al-Mateen, M. Hood, D. Trippel, S. J. Insalaco, R. K. Otto, and K. J. Vitikainen Cerebral Embolism From Atrial Myxoma in Pediatric Patients Pediatrics, August 1, 2003; 112(2): e162 - 167. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. G.P. Nucifora and W. P. Dillon MR Diagnosis of Myxomatous Aneurysms: Report of Two Cases AJNR Am. J. Neuroradiol., August 1, 2001; 22(7): 1349 - 1352. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N.A. Robbin, P. Landless, K. Cooper, and V.U. Fritz Myxoma in the Carotid Artery: Myxomatous Occlusion of Internal Carotid Artery Stroke, February 1, 1997; 28(2): 456 - 458. [Abstract] [Full Text]
|
|
|
|
|
|
Cardiogenic Brain Embolism: The Second Report of the Cerebral Embolism Task Force Arch Neurol, July 1, 1989; 46(7): 727 - 743. [Abstract] [PDF]
|
|