This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Suzuki, R. Articles by Inaba, Y. Search for Related Content PubMed PubMed Citation Articles by Suzuki, R. Articles by Inaba, Y.

Stroke, Vol 19, 322-325, Copyright © 1988 by American Heart Association

ARTICLES

Serial changes in focal hyperemia associated with hypertensive putaminal hemorrhage

R Suzuki, K Ohno, Y Matsushima and Y Inaba
Department of Neurosurgery, Tokyo Medical and Dental University, Japan.

Seventeen separate xenon-enhanced computed tomographic images were performed in seven patients with hypertensive putaminal hemorrhage. Regional cerebral blood flow maps were then computed and assessed. All patients were categorized as being of good recovery potential, with moderate-sized hematomas, and all were treated conservatively. The regional cerebral blood flow assessments were scheduled within 4 days after, 2 weeks after, and less than 25 days after the ictus. The initial decrease in hemispheric blood flow ipsilateral to the side of the hematoma was calculated as the ratio of ipsilateral to contralateral hemispheric blood flow and was correlated with the size of the hematoma; that is, the larger the hematoma, the greater the decrease in the ratio of ipsilateral to contralateral hemispheric blood flow. The decrease persisted for 1 month. The mean of the ratio at 2 weeks after onset was 70%, the lowest during follow-up. All cases examined within 4 days after onset demonstrated perihematomatous focal hyperemia, or "luxury perfusion," which accounted for the delayed decrease. The same tissue that had previously shown hyperemia showed decreased regional cerebral blood flow 2 weeks after onset. Our results demonstrate that the luxury perfusion syndrome caused the secondary brain damage even in the cases that were in relatively good condition. The feasibility of treatment can be assessed by considering these results.

This article has been cited by other articles:

				T. D. Ardizzone, A. Lu, K. R. Wagner, Y. Tang, R. Ran, and F. R. Sharp Glutamate Receptor Blockade Attenuates Glucose Hypermetabolism in Perihematomal Brain After Experimental Intracerebral Hemorrhage in Rat Stroke, November 1, 2004; 35(11): 2587 - 2591. [Abstract] [Full Text] [PDF]