Stroke, Vol 19, 503-506, Copyright © 1988 by American Heart Association
JW Berkelbach van der Sprenkel and CA Tulleken
The study of the relation between behavior, cerebral blood flow, and
metabolism in animal models of cerebral ischemia has gained interest in the
last 10 years. The most suitable models are those with the fewest side
effects. One-sided blindness caused by decompression of the eye and
coagulation of the optic nerve has been an inevitable side effect of
transorbital occlusion of the middle cerebral artery. The postorbital
technique is a new surgical approach to the middle cerebral artery that
leaves the intraorbital structures intact. After resection of the
postorbital processes and gentle retraction of the eye, the optic foramen
is approached with the help of an operating microscope. This approach is
possible because cats have no lateral bony orbital wall. A subperiostal
approach to the optic foramen is made, after which the optic foramen is
enlarged. Opening of the dura gives access to the middle cerebral artery in
the same way as the transorbital approach. In this way, occlusion of the
middle cerebral artery is possible with minimal impairment of vision.
ARTICLES
The postorbital approach to the middle cerebral artery in cats
Department of Neurosurgery, University Hospital, Utrecht, The Netherlands.
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