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(Stroke. 1971;2:160.)
© 1971 American Heart Association, Inc.

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Long-Term Prognosis of Transient Cerebral Ischemic Attacks

JOHN C. GOLDNER M.D.¹; JACK P. WHISNANT M.D.²; WILLIAM F. TAYLOR PH.D.³

¹ Mayo Graduate School of Medicine, University of Minnesota, Rochester: Resident in Neurology
² Mayo Clinic and Mayo Foundation: Department of Neurology
³ Department of Medical Statistics, Epidemiology and Population Genetics

A 15-year follow-up of 140 patients who had transient cerebral ischemic attacks and were first seen at the Mayo Clinic for this complaint in 1950 through 1954 is reported. There was no significant difference in mortality related to sex or location of residence. Patients hypertensive at onset of symptoms had no significant increase in mortality compared to normotensive patients but the survival trend favored normotensive patients. Probability of surviving 15 years was significantly less than expected for patients less than 65 years old. Patients who were 65 or older at their first attack had a survival similar to that of the standard population. The difference between the expected and observed 15-year survivals for patients with primarily motor symptoms was about the same as that difference for patients with primarily sensory symptoms. Information concerning stroke occurrence was incomplete but 37% of local residents are known to have had a stroke, a higher rate than expected. Among patients who died during this study, 50% died of a cardiac cause and 36% died of a stroke.

Key Words: stroke • hypertension • cause of death • survival • motor symptoms • natural history • expected survival • sensory symptoms • mortality

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