Stroke, Vol 21, 1567-1572, Copyright © 1990 by American Heart Association
N Handa, M Matsumoto, H Maeda, H Hougaku, S Ogawa, R Fukunaga, S Yoneda, K Kimura and T Kamada
We investigated the prevalence of carotid atherosclerosis, including mild
early lesions, and its association with cervical bruits and various risk
factors (age, male sex, hypertension, hyperlipidemia, diabetes mellitus,
obesity, and cigarette smoking) in 232 consecutive Japanese patients.
High-resolution real-time B-mode ultrasonography was performed to determine
the extent of atherosclerosis, and it was quantified by using a scoring
system. The prevalence of carotid atherosclerosis was 49%, 59%, and 41% in
all 232 patients, the 100 symptomatic patients, and the 132 asymptomatic
patients, respectively. Although carotid lesions were detected frequently
(87%) in the 30 patients with cervical bruits, bruits were noted in only
30% of the 88 examined patients with carotid atherosclerosis. Independent
risk factors for carotid atherosclerosis in these patients were found to be
age, male sex, and hyperlipidemia; diabetes mellitus was a possible risk
factor for carotid atherosclerosis. Our study did not show a close
association between hypertension and carotid atherosclerosis, and this
might be caused by the high prevalence of hypertension in our patients. Our
findings suggest an increasing prevalence of carotid atherosclerosis in the
Japanese, though this should be confirmed in a population-based study. Our
study demonstrates the clinical usefulness of high-resolution B-mode
ultrasonography for the evaluation of early carotid atherosclerosis.
ARTICLES
Ultrasonic evaluation of early carotid atherosclerosis
First Department of Internal Medicine, Osaka University Medical School, Japan.
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