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Stroke, Vol 21, 476-479, Copyright © 1990 by American Heart Association
RK Fredericks, TD Thomas, DS Lefkowitz and BT Troost
We identified 60 patients (42 men and 18 women with an average age of 62.6
years) with angiographically documented carotid stenoses of greater than or
equal to 95%; a string sign was demonstrated in 28. Twenty of the 60
patients (33%) were asymptomatic on presentation, 26 (43%) had hemispheric
transient ischemic attacks, 21 (35%) had amaurosis fugax, and nine (15%)
had previous ipsilateral infarctions. Demographics, mode of presentation,
and prevalence of atherosclerotic risk factors were not significantly
different between patients with and without a string sign. Doppler
frequencies recorded in patients with a string sign were less than 6 or
greater than 16 KHz. Real-time ultrasonography imaged a patent lumen in all
but three cases with a string sign. Surgery was performed in 26 patients
with a string sign and in 21 patients without a string sign. The rate of
major perioperative complications was not influenced by the presence of a
string sign, contralateral extracranial stenosis, or ipsilateral siphon
stenosis. Average lumen size of the endarterectomy specimens was 0.94 mm in
those with and 1.7 mm in those without a string sign. We conclude that
combined noninvasive testing has a sensitivity of 83% for demonstrating a
residual lumen in patients with greater than or equal to 95% carotid
stenosis and that the angiographic string sign does not affect the mode of
presentation or surgical outcome of these patients.
ARTICLES
Implications of the angiographic string sign in carotid atherosclerosis
Department of Neurology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina 27103.
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