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Stroke, Vol 22, 431-436, Copyright © 1991 by American Heart Association

ARTICLES

Cerebral infarction verified by cranial computed tomography and prognosis for survival following transient ischemic attack

GW Evans, G Howard, KE Murros, LA Rose and JF Toole
Department of Public Health Sciences, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, N.C. 27103.

Of 564 consecutive patients with transient ischemic attack, 350 (62%) had cranial computed tomography performed. Except for date of admission and smoking history, there were few differences between the patients evaluated with computed tomography and the 214 who were not. Cerebral infarcts were found in 59 (17%) of the 350 tomographic evaluations. Previous clinically diagnosed stroke, older age, and male sex were all significantly associated with the occurrence of tomographically verified infarcts (p less than 0.05). After controlling for stroke history and other important covariates, patients with tomographically verified infarcts had significantly shorter survival times than did patients without evidence of infarction on computed tomography (p = 0.035). Thus, cranial computed tomography findings appear to have important prognostic value for estimating survival following transient ischemic attack.

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