This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Montalban, J. Articles by Hughes, G. R. Search for Related Content PubMed PubMed Citation Articles by Montalban, J. Articles by Hughes, G. R.

Stroke, Vol 22, 750-753, Copyright © 1991 by American Heart Association

ARTICLES

Antiphospholipid antibodies in cerebral ischemia

J Montalban, A Codina, J Ordi, M Vilardell, MA Khamashta and GR Hughes
Servei de Neurologia, Hospital General Vall d'Hebron, Barcelona, Spain.

In a 2-year prospective study of 146 patients with cerebral ischemia, we compared vascular risk factors for stroke with clinical and laboratory findings, particularly antiphospholipid antibodies. Ten patients (6.8%) were positive for at least one antiphospholipid antibody; one patient had systemic lupus erythematosus, one had rheumatoid arthritis, and the remaining eight fulfilled criteria for the diagnosis of primary antiphospholipid syndrome. These patients were predominantly male, not necessarily young, and 50% of them did not have any other vascular risk factors; there were no significant clinical or paraclinical differences between these patients and those without antiphospholipid antibodies. Outcome in the 10 patients was good, and platelet antiaggregating drugs proved to be useful in preventing further cerebrovascular ischemic events in our patients.

This article has been cited by other articles:

				W. H. Chen Anti-beta2-Glycoprotein I Antibody and Hypertension in Cerebral Ischemia Clinical and Applied Thrombosis/Hemostasis, January 1, 2004; 10(1): 55 - 60. [Abstract] [PDF]

				M. M Brown IDENTIFICATION AND MANAGEMENT OF DIFFICULT STROKE AND TIA SYNDROMES J. Neurol. Neurosurg. Psychiatry, April 1, 2001; 70(90001): 17i - 22. [Full Text]

				C. D. Bushnell and L. B. Goldstein Diagnostic Testing for Coagulopathies in Patients With Ischemic Stroke Stroke, December 1, 2000; 31(12): 3067 - 3078. [Abstract] [Full Text] [PDF]

				P. Verro, S. R. Levine, and G. E. Tietjen Cerebrovascular Ischemic Events With High Positive Anticardiolipin Antibodies Stroke, November 1, 1998; 29(11): 2245 - 2253. [Abstract] [Full Text] [PDF]

				P. R.J. Ames Medical Perspective Antiphospholipid Antibodies, Thrombosis and Atherosclerosis in Systemic Lupus Erythematosus: a Unifying 'Membrane Stress Syndrome' Hypothesis Lupus, October 1, 1994; 3(5): 371 - 377. [PDF]

				G. Rivier, M. T. Herranz, M. A. Khamashta, and G. R.V. Hughes Thrombosis and Antiphospholipid Syndrome: a Preliminary Assessment of Three Antithrombotic Treatments Lupus, April 1, 1994; 3(2): 85 - 90. [Abstract] [PDF]

				J. Etherington, A. Cooper, and N. Buchanan Case Report Antiphospholipid Syndrome in Rheumatoid Arthritis Presenting with Sensorineural Deafness Lupus, February 1, 1994; 3(1): 63 - 64. [Abstract] [PDF]