Stroke, Vol 22, 1155-1163, Copyright © 1991 by American Heart Association
DH O'Leary, JF Polak, SK Wolfson Jr, MG Bond, W Bommer, S Sheth, BM Psaty, AR Sharrett and TA Manolio
Carotid sonography is being performed on more than 5,000 participants in
the Cardiovascular Health Study, a prospective, multicenter study of
cardiovascular disease in men and women aged 65 years and older. The
sonographic methods used to examine and measure the extracranial carotid
arteries are described. Initial validation studies were performed on 61
subjects with a mean age of 68.6 years. Analysis of within- and
between-sonographer differences and between-reader differences were
performed for selected variables. In general, the mean absolute differences
for within- and between-sonographer comparisons were small, with even less
variability between readers. Variability was less for the common carotid
artery than for the internal carotid artery. These data suggest that
carotid sonography is a reliable and reproducible method for use in the
study of carotid atherosclerosis in population studies.
ARTICLES
Use of sonography to evaluate carotid atherosclerosis in the elderly. The Cardiovascular Health Study. CHS Collaborative Research Group
Department of Radiology, Brigham and Women's Hospital, Boston, Mass.
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