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Stroke, Vol 23, 295-297, Copyright © 1992 by American Heart Association

ARTICLES

Cerebral infarction in young men with nephrotic syndrome

JL Fuh, MM Teng, WC Yang and HC Liu
Department of Radiology, Veterans General Hospital-Taipei, Taiwan.

BACKGROUND AND PURPOSE: Thrombosis is one of the main complications of nephrotic syndrome; however, cerebral infarction associated with nephrotic syndrome has been rarely reported. SUMMARY OF REPORT: We describe acute cerebral infarction in two young men with nephrotic syndrome. Both had a hypercoagulable state based on hemostatic studies. By retrospectively reviewing the medical records of the past 10 years at our hospital, we found an additional five cases of cerebral infarction with nephrotic syndrome. Two of the patients were found to have nephrotic syndrome during admission for stroke. CONCLUSIONS: Hypercoagulability may be the major contributing factor of cerebral infarction in patients with nephrotic syndrome.