Stroke, Vol 24, 931-939, Copyright © 1993 by American Heart Association
LW Niessen, JJ Barendregt, L Bonneux and PJ Koudstaal
BACKGROUND AND PURPOSE: Trends in stroke incidence and survival determine
changes in stroke morbidity and mortality. This study examines the extent
of the incidence decline and survival improvement in the Netherlands from
1979 to 1989. In addition, it projects future changes in stroke morbidity
during the period 1985 to 2005, when the country's population will be
aging. METHODS: A state-event transition model is used, which combines
Dutch population projections and existing data on stroke epidemiology.
Based on the clinical course of stroke, the model describes historical
national age- and sex-specific hospital admission and mortality rates for
stroke. It extrapolates observed trends and projects future changes in
stroke morbidity rates. RESULTS: There is evidence of a continuing
incidence decline. The most plausible rate of change is an annual decline
of -1.9% (range, -1.7% to -2.1%) for men and -2.4% (range, -2.3% to -2.8%)
for women. Projecting a constant mortality decline, the model shows a 35%
decrease of the stroke incidence rate for a period of 20 years. Prevalence
rates for major stroke will decline among the younger age groups but
increase among the oldest because of increased survival in the latter. In
absolute numbers this results in an 18% decrease of acute stroke episodes
and an 11% increase of major stroke cases. CONCLUSIONS: The increase in
survival cannot fully explain the observed mortality decline and,
therefore, a concomitant incidence decline has to be assumed. Aging of the
population partially outweighs the effect of an incidence decline on the
total burden of stroke. Increase in cardiovascular survival leads to a
further increase in major stroke prevalence among the oldest age groups.
ARTICLES
Stroke trends in an aging population. The Technology Assessment Methods Project Team
Department of Public Health and Social Medicine, Erasmus University, Rotterdam, The Netherlands.
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