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Stroke, Vol 25, 214-216, Copyright © 1994 by American Heart Association

ARTICLES

Basilar artery occlusion in a young patient with Wegener's granulomatosis

JM Savitz, MA Young and RR Ratan
Department of Rehabilitation Medicine, Johns Hopkins University School of Medicine, Baltimore, Md.

BACKGROUND AND PURPOSE--Stroke is an uncommon sequela of Wegener's granulomatosis, resulting primarily from vasculitic infiltration of small to medium-sized vessels. We describe a young patient with Wegener's granulomatosis and basilar artery occlusion. CASE DESCRIPTION- -A 26-year-old man with histopathologically confirmed Wegener's granulomatosis suffered a brain stem stroke 24 hours after open lung biopsy. Angiography revealed midbasilar artery occlusion. CONCLUSIONS-- Patients with Wegener's granulomatosis may experience premature large cerebral vessel occlusion. Putative etiologies in our patient include vasculitis, postoperative hypercoagulability, and/or intraoperative neck positioning leading to embolization.

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