Stroke, Vol 25, 2120-2125, Copyright © 1994 by American Heart Association
G Howard, R Anderson, P Sorlie, V Andrews, E Backlund and GL Burke
BACKGROUND AND PURPOSE: Although US blacks are known to have an excess
stroke mortality compared with US whites, little is known about the stroke
burden of the Hispanic white population. This report will provide estimates
of the relative burden of stroke mortality in the US black and Hispanic
population relative to the white population and examine the consistency of
this relation across age. METHODS: Data were from participants aged > 45
years from the National Longitudinal Mortality Study. There were 1844
stroke deaths among 239,734 non- Hispanic whites, 46 deaths among 12,527
Hispanic whites, and 234 deaths among 23,468 black participants. Standard
statistical methods were used to examine the ethnic differences in stroke
mortality. RESULTS: The hazard ratios for black men and women (relative to
non-Hispanic whites) were nearly identical, at > 4.0 at age 45 but
marginally < 1.0 by age 85. For both Hispanic men and women, the hazard
ratios (relative to non- Hispanic whites) were approximately 1.0 at age 45
but were marginally significantly < 1.0 at older ages. The ethnic
differences in stroke death rates reveal differences in age distributions
of age at fatal stroke between these groups. Approximately 6% of fatal
strokes for non- Hispanic whites occurred before age 60, whereas > 15%
occurred in both Hispanic whites and blacks. CONCLUSIONS: These results
suggest that (1) for Hispanics, stroke risk is similar to that for
non-Hispanic whites at young ages but is marginally lower at older ages,
(2) the excess stroke mortality in blacks mainly occurs at younger ages
(between 45 and 55 years), and (3) the relation between stroke risk for
blacks and Hispanics relative to whites is similar by sex. The impact of
age on relative stroke mortality would argue against simple age adjustment
for describing ethnic differences in stroke mortality. Finally,
proportionally, more strokes occur at older ages in non-Hispanic whites
than in either US blacks or Hispanic whites.
ARTICLES
Ethnic differences in stroke mortality between non-Hispanic whites, Hispanic whites, and blacks. The National Longitudinal Mortality Study
Department of Public Health Sciences, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC 27157-1063.
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