(Stroke. 1995;26:1764-1767.)
© 1995 American Heart Association, Inc.
Articles |
Predictors of Early Deterioration and Mortality in Black Americans With Spontaneous Intracerebral Hemorrhage
From the Departments of Neurology (A.I.Q., K.S., C.B., D.L.B., B.M., M.R.F.), Medicine (E.J.W.), and Neurosurgery (A.R.C.), Emory University School of Medicine, Atlanta, Ga.
Correspondence to Michael R. Frankel, MD, Chief of Neurology, Grady Memorial Hospital, 80 Butler St SE, PO Box 26036, Atlanta, GA 30335.
Background and Purpose Black Americans with spontaneous intracerebral hemorrhage (SICH) may have unique clinical characteristics that affect outcome. The aim of this study was to determine the prognostic value of clinical characteristics and initial CT scan for outcome in black Americans with SICH.
Methods Clinical and demographic data were extracted from the
charts of 182 consecutive black Americans admitted for SICH diagnosed
by clinical criteria and initial CT scan. Hemorrhage volumes
were calculated from admission CT scans by a computerized method.
Univariate and multiple logistic regression
analyses were performed to determine independent predictors of
early deterioration (defined as a decrease from an initial Glasgow Coma
Scale score >12 by 
4 points within 24 hours from
presentation) and mortality.
Results Both hemorrhage volume and
ventricular extension were significant, independent
predictors of early deterioration (odds ratio [OR], 6.78; 95%
confidence interval [CI], 1.89 to 24.35 and OR, 4.67; 95% CI, 1.30
to 16.72, respectively) and mortality (OR, 6.66; 95% CI, 2.85 to 15.58
and OR, 4.23; 95% CI, 1.82 to 9.82, respectively). A Glasgow Coma
Scale score 
12 also predicted mortality (OR, 3.23; 95% CI, 1.46 to
7.14). Initial mean arterial pressure was not an
independent predictor of early deterioration or mortality.
Conclusions Hemorrhage volume and ventricular extension are the best predictors of early deterioration and mortality in black Americans with SICH.
Key Words: blacks • intracerebral hemorrhage • mortality • racial differences • tomography
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