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(Stroke. 1997;28:1607-1609.)
© 1997 American Heart Association, Inc.

Articles

Venous Microembolic Signals Detected in Patients With Cerebral Sinus Thrombosis

José Manuel Valdueza, MD; Lutz Harms, MD; Florian Doepp; Jürgen Koscielny, MD Karl Max Einhäupl, MD

From the Department of Neurology and Institute of Transfusion (J.K.), University Hospital Charité, Humboldt University, Berlin, Germany.

Background and Purpose We sought to assess the usefulness of the Doppler technique in the monitoring of microembolic signals in the main venous outflow pathways in superior sagittal sinus thrombosis.

Methods Transcranial Doppler ultrasound was performed with a range-gated 2-MHz transducer in 6 patients with superior sagittal sinus thrombosis, in 5 subjects with platelet hyperaggregability, and in 20 healthy volunteers. Emboli monitoring was performed mainly in one distal internal jugular vein for 10 to 15 minutes.

Results Three of the six patients (50%) with superior sagittal sinus thrombosis had microemboli. None of the patients with platelet hyperaggregation or healthy volunteers revealed microemboli.

Conclusions Microemboli can be found in superior sagittal sinus thrombosis by Doppler ultrasound. Their prognostic significance remains to be determined.

Key Words: Doppler • embolism • sinus thrombosis