From the Departments of Neurology (J.B., T.B., R.M., J.G., D.M., L.M.),
Emergency Medicine (R.K., A.P.), and Environmental Health (J.K., R.S.),
University of Cincinnati Medical Center, Cincinnati, Ohio.
Correspondence to Joseph Broderick, MD, University of Cincinnati Medical Center, Department of Neurology, 231 Bethesda Ave, Room 4010, Cincinnati, OH 45267-0525. E-mail broderjp{at}ucsmtp.edu
Background and PurposeThe Greater
Cincinnati/Northern Kentucky Stroke Study was designed to be the first
large, population-based metropolitan study of temporal trends in stroke
incidence rates and outcome within a biracial population.
MethodsWe are identifying all hospitalized and autopsied cases
of stroke and transient ischemic attack (TIA) among the 1.3
million inhabitants of a five-county region of Greater
Cincinnati/Northern Kentucky for the period 7/1/936/30/94. We have
already prospectively monitored for out-of-hospital stroke and TIAs for
this same time period at 128 screening sites, including a random sample
of all primary care physicians and nursing homes in the region. We have
already identified all hospitalized and autopsied cases of stroke and
TIA among blacks for 1/1/936/30/93 and report preliminary incidence
rates for this 6-month period.
ResultsThe overall incidence rate for all first-ever
hospitalized or autopsied stroke (excluding TIAs) among blacks in the
Greater Cincinnati region was 288 per 100 000 (95% CI, 250 to 325,
age- and sex-adjusted to 1990 US population). The overall incidence
rate for first-ever and recurrent stroke (excluding TIAs) was 411 per
100 000 (95% CI, 366 to 456). By comparison, the overall incidence
rate of first-ever stroke among whites in Rochester, Minn, during the
period 19851989 was 179 per 100 000 (95% CI, 164 to 194, age-
and-sex adjusted to 1990 US population). The incidence rates among
blacks in Greater Cincinnati were substantially greater than the rates
among whites in Rochester, Minn, for all age categories except ages 75
and older, for which the rates were similar.
ConclusionsWe conservatively estimate that 731 100 first-ever
or recurrent strokes occurred in the United States during 1996. Studies
of first-ever as well as total stroke among biracial and
representative populations are critical for
understanding temporal trends in the incidence rate and the burden of
stroke in the US population.
© 1998 American Heart Association, Inc.
Original Contributions
The Greater Cincinnati/Northern Kentucky Stroke Study
Preliminary First-Ever and Total Incidence Rates of Stroke Among Blacks
Key Words: cerebral infarction epidemiology intracerebral hemorrhage racial differences subarachnoid hemorrhage
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