From the Departments of Medicine (W.H.C., D.S.W.H., S.L.H., R.T.F.C.) and
Surgery (S.W.K.C.), The University of Hong Kong, Queen Mary Hospital, Hong
Kong.
Correspondence to David Sai Wah Ho, MD, Associate Professor of Medicine, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong. E-mail dswho{at}hkucc.hku.hk
Background and Purpose—Chinese have
been reported to have an extremely low prevalence rate of carotid and
vertebral artery disease in comparison with whites. Previous studies,
however, have been limited to general hospital stroke admission or
postmortem series and were prone to selection bias. Extracranial
cerebrovascular disease (ECCVD) is associated with coronary
artery disease (CAD) in whites. Data associating ECCVD with CAD in
Chinese patients are not available.
Methods—We studied 153 consecutive Chinese patients with
angiographically documented CAD. Duplex ultrasonography was performed
to identify any underlying extracranial carotid and vertebral artery
disease. Patient demographics; vascular risk factors; history of
myocardial infarction, transient ischemic attack (TIA) or
stroke; concomitant peripheral vascular disease (PVD);
degree of left ventricular dysfunction; and extent and
severity of CAD were also noted and analyzed.
Results—Significant (
Conclusions—Significant ECCVD is not uncommon in Chinese patients
with CAD, and the prevalence is comparable with that reported in white
populations. Patients with a history of diabetes, hypertension, TIA,
stroke, and PVD are more likely to have concomitant ECCVD.
© 1998 American Heart Association, Inc.
Original Contributions
Prevalence of Extracranial Carotid and Vertebral Artery Disease in Chinese Patients With Coronary Artery Disease
50%) stenosis of one or more of
the extracranial cerebral arteries was found in 32 patients (21%). The
internal and external carotid arteries were involved in 17 of 153
patients (11%) and 19 of 153 patients (12%), respectively. The
vertebral artery was involved in 9 of 153 patients (6%) and the common
carotid artery in 3 of 153 (2%). Diabetes mellitus, hypertension, a
history of TIA or stroke, and PVD were significantly associated with
the presence of ECCVD.
Key Words: carotid artery diseases • cerebral arteries • Chinese • coronary artery disease • vertebral artery
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