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(Stroke. 1972;3:57.)
© 1972 American Heart Association, Inc.

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Relationship of Serial Measurements of Cerebral Hemodynamics to Prognosis in Patients with Hypertension and Cerebrovascular Disease

Saburo Yamaoka M.D.¹; Yasuyuki Takagi M.D.²; Toshihiro Okada M.D.¹; Yoshio Saito M.D.³

¹ Department of Internal Medicine, Keiyu Hospital, 47 Yamashita-cho, Naka-ku, Yokohama, Kanagawa Prefecture, Japan
² Tokyo Saiseikai Central Hospital, #1-4, Mita, Minato-ku, Tokyo, Japan
³ Department of Internal Medicine, Keiyu Hospital 47 Yamashita-cho, Naka-ku, Yokohama, Kanagawa Prefecture, Japan

Baseline and follow-up measurements of cerebral hemodynamics were performed in hypertensive patients by the N₂O method with a certain time interval. A tendency for some decrease in the CBF was noted, but the difference was not statistically significant.

Twelve hypertensive patients suffered from a stroke during the period of observation. The CBF values prior to the stroke varied so widely that there was no predictive value from these measurements.

The decrease in CBF in a mild case of cerebral infarction is slight and is followed by little fluctuation. The decrease in a case of moderate severity is marked but returns to normal in two to five months. Clinically severe cases of infarction and hemorrhage are also characterized by a marked decrease in CBF, but this decrease of infarcted cases may be irreversible.

A higher incidence of recurrent infarction is noted in those patients in whom recovery of CBF following a stroke is poorest. This is most apparent in those patients suffering a recurrence within one year.

Key Words: preapoplectic cerebral circulation • postapoplectic cerebral circulation