(Stroke. 1999;30:363-370.)
© 1999 American Heart Association, Inc.
Original Contributions |
Stroke Incidence and Case Fatality in Southern Greece
The Arcadia Stroke Registry
From the Department of Clinical Therapeutics, University of Athens School of Medicine, Alexandra Hospital, Athens, Greece (K.N.V., G.S.S., S.S.); Julius Center for Patient Oriented Research, University Medical Center Utrecht, Utrecht, Netherlands (M.L.B., D.E.G.); Department of Medicine, General Arcadia Hospital Evaggelistria, Tripoli, Greece (P.K.T.); and Department of Neurology, University of Athens School of Medicine, Aiginition Hospital, Athens, Greece (V.P.Z.).
Correspondence to Kostas N. Vemmos, MD, Acute Stroke Unit, Department of Clinical Therapeutics, University of Athens School of Medicine, Alexandra Hospital, 80 Vasilissis Sofias and Lourou Str, 11528, Athens, Greece. E-mail vemmosk{at}ath.forthnet.gr
Background and Purpose—For Greece, information on incidence of stroke and distribution of type of stroke has not been reported. We determined the incidence of first-ever stroke in men and women, the incidence of stroke by type, and the associated case fatality.
Methods—A population-based registry was established in the Arcadia province, located in eastern central Peloponessos, in the southern part of Greece. Between November 1, 1993, and October 31, 1995, all subjects with a first-ever stroke were identified. For case ascertainment, information from death certificates, hospital records, public health centers, and general practitioners was used.
Results—During a 24-month period, 555 subjects with a first-ever
stroke were registered. The incidence rates (per 100 000) by age group
(18 to 34, 35 to 44, 45 to 54, 55 to 64, 65 to 74, 75 to 84, 
85
years) for men were 5, 31, 113, 240, 662, 1275, and 3218, respectively.
For women, the rates were 11, 18, 48, 196, 478, 1166, and 2137,
respectively. Age- and sex-standardized to the European
population, the annual incidence rate for subjects aged 45 to 84 years
was 319.4/100 000 (95% CI, 283 to 356). In men, cerebral infarction
was diagnosed in 81% of cases, intracerebral
hemorrhage in 16%, and subarachnoid hemorrhage
in 2%. For women, these figures were 85%, 12%, and 3%,
respectively. The 28-day case fatality rate was 26.6% (95% CI, 22.9%
to 30.2%), with no differences between men and women. Case-fatality
increased with age and was higher for intracerebral
hemorrhage than for cerebral infarction.
Conclusions—The incidence of stroke in our population-based study ranks low part compared with other European studies. The distribution of stroke types and case fatality rate appear to be similar to those of other industrialized countries.
Key Words: incidence • fatal outcome • Greece • mortality
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