Donate Help Contact The AHA Sign In Home
American Heart Association
Stroke
Search: search_blue_button Advanced Search
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Diringer, M. N.
Right arrow Articles by Dromerick, A. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Diringer, M. N.
Right arrow Articles by Dromerick, A. W.
Related Collections
Right arrow Health policy and outcome research
Right arrow Embolic stroke

(Stroke. 1999;30:724-728.)
© 1999 American Heart Association, Inc.


Original Contributions

Predictors of Acute Hospital Costs for Treatment of Ischemic Stroke in an Academic Center

M. N. Diringer, MD; D. F. Edwards, PhD; D. T. Mattson, BS; P. T. Akins, MD; C. W. Sheedy, RN; C. Y. Hsu, MD, PhD A. W. Dromerick, MD

From the Department of Neurology (M.N.D., D.F.E., P.T.A., C.W.S., A.W.D.) and Program in Occupational Therapy (M.N.D., D.F.E., A.W.D.), Washington University School of Medicine, St Louis, Mo.

Background and Purpose—We sought to determine predictors of acute hospital costs in patients presenting with acute ischemic stroke to an academic center using a stroke management team to coordinate care.

Methods—Demographic and clinical data were prospectively collected on 191 patients consecutively admitted with acute ischemic stroke. Patients were classified by insurance status, premorbid modified Rankin scale, stroke location, stroke severity (National Institutes of Health Stroke Scale score), and presence of comorbidities. Detailed hospital charge data were converted to cost by application of department-specific cost-to-charge ratios. Physician's fees were not included. A stepwise multiple regression analysis was computed to determine the predictors of total hospital cost.

Results—Median length of stay was 6 days (range, 1 to 63 days), and mortality was 3%. Median hospital cost per discharge was $4408 (range, $1199 to $59 799). Fifty percent of costs were for room charges, 19% for stroke evaluation, 21% for medical management, and 7% for acute rehabilitation therapies. Sixteen percent were admitted to an intensive care unit. Length of stay accounted for 43% of the variance in total cost. Other independent predictors of cost included stroke severity, heparin treatment, atrial fibrillation, male sex, ischemic cardiac disease, and premorbid functional status.

Conclusions—We conclude that the major predictors of acute hospital costs of stroke in this environment are length of stay, stroke severity, cardiac disease, male sex, and use of heparin. Room charges accounted for the majority of costs, and attempts to reduce the cost of stroke evaluation would be of marginal value. Efforts to reduce acute costs should be monitored for potential cost shifting or a negative impact on quality of care.


Key Words: costs and cost analysis • outcome • stroke, ischemic • stroke management




This article has been cited by other articles:


Home page
CirculationHome page
W. Rosamond, K. Flegal, K. Furie, A. Go, K. Greenlund, N. Haase, S. M. Hailpern, M. Ho, V. Howard, B. Kissela, et al.
Heart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Circulation, January 29, 2008; 117(4): e25 - e146.
[Full Text] [PDF]


Home page
StrokeHome page
H.-C. Lin, S. Xirasagar, C.-H. Chen, C.-C. Lin, and H.-C. Lee
Association Between Physician Volume and Hospitalization Costs for Patients With Stroke in Taiwan: A Nationwide Population-Based Study
Stroke, May 1, 2007; 38(5): 1565 - 1569.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
W. Rosamond, K. Flegal, G. Friday, K. Furie, A. Go, K. Greenlund, N. Haase, M. Ho, V. Howard, B. Kissela, et al.
Heart Disease and Stroke Statistics--2007 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Circulation, February 6, 2007; 115(5): e69 - e171.
[Full Text] [PDF]


Home page
StrokeHome page
M. Moodie, D. Cadilhac, D. Pearce, C. Mihalopoulos, R. Carter, S. Davis, G. Donnan, and for the SCOPES Study Group
Economic Evaluation of Australian Stroke Services: A Prospective, Multicenter Study Comparing Dedicated Stroke Units With Other Care Modalities
Stroke, November 1, 2006; 37(11): 2790 - 2795.
[Abstract] [Full Text] [PDF]


Home page
NeurologyHome page
M. W. Russell, A. V. Joshi, P. J. Neumann, L. Boulanger, and J. Menzin
Predictors of hospital length of stay and cost in patients with intracerebral hemorrhage.
Neurology, October 10, 2006; 67(7): 1279 - 1281.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
R. Luengo-Fernandez, A. M. Gray, and P. M. Rothwell
Population-Based Study of Determinants of Initial Secondary Care Costs of Acute Stroke in the United Kingdom
Stroke, October 1, 2006; 37(10): 2579 - 2587.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
T. Thom, N. Haase, W. Rosamond, V. J. Howard, J. Rumsfeld, T. Manolio, Z.-J. Zheng, K. Flegal, C. O'Donnell, S. Kittner, et al.
Heart Disease and Stroke Statistics--2006 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Circulation, February 14, 2006; 113(6): e85 - e151.
[Full Text] [PDF]


Home page
ANN INTERN MEDHome page
M. D. Schleinitz and P. A. Heidenreich
A Cost-Effectiveness Analysis of Combination Antiplatelet Therapy for High-Risk Acute Coronary Syndromes: Clopidogrel plus Aspirin versus Aspirin Alone
Ann Intern Med, February 15, 2005; 142(4): 251 - 259.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
A. I. Qureshi, M. F. K. Suri, J. F. Kirmani, and A. A. Divani
The Relative Impact of Inadequate Primary and Secondary Prevention on Cardiovascular Mortality in the United States
Stroke, October 1, 2004; 35(10): 2346 - 2350.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
T. Rundek, K. Nielsen, S. Phillips, K. C. Johnston, M. Hux, D. Watson, and for the GAIN Americas Investigators
Health Care Resource Use After Acute Stroke in the Glycine Antagonist in Neuroprotection (GAIN) Americas Trial
Stroke, June 1, 2004; 35(6): 1368 - 1374.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
K.-C. Chang and M.-C. Tseng
Costs of Acute Care of First-Ever Ischemic Stroke in Taiwan
Stroke, November 1, 2003; 34 (11): e219 - e221.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
J. S. Elkins and S. C. Johnston
Thirty-Year Projections for Deaths From Ischemic Stroke in the United States
Stroke, September 1, 2003; 34(9): 2109 - 2112.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
Y. Yoneda, T. Uehara, H. Yamasaki, Y. Kita, M. Tabuchi, and E. Mori
Hospital-Based Study of the Care and Cost of Acute Ischemic Stroke in Japan
Stroke, March 1, 2003; 34(3): 718 - 724.
[Abstract] [Full Text] [PDF]


Home page
NeurologyHome page
W.S. Burgin, L. Staub, W. Chan, PhD;, T.H. Wein, R.A. Felberg, J.C. Grotta, A.M. Demchuk, S.L. Hickenbottom, and L.B. Morgenstern
Acute stroke care in non-urban emergency departments
Neurology, December 11, 2001; 57(11): 2006 - 2012.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
D. W. Krieger, M. A. De Georgia, A. Abou-Chebl, J. C. Andrefsky, C. A. Sila, I. L. Katzan, M. R. Mayberg, and A. J. Furlan
Cooling for Acute Ischemic Brain Damage (COOL AID): An Open Pilot Study of Induced Hypothermia in Acute Ischemic Stroke
Stroke, August 1, 2001; 32(8): 1847 - 1854.
[Abstract] [Full Text] [PDF]


Home page
NeurologyHome page
S. D. Reed, D. K. Blough, K. Meyer, and J. G. Jarvik
Inpatient costs, length of stay, and mortality for cerebrovascular events in community hospitals
Neurology, July 24, 2001; 57(2): 305 - 314.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
D. E. Briggs, R. A. Felberg, M. D. Malkoff, P. Bratina, and J. C. Grotta
Should Mild or Moderate Stroke Patients Be Admitted to an Intensive Care Unit?
Stroke, April 1, 2001; 32(4): 871 - 876.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
M. Lamassa, A. Di Carlo, G. Pracucci, A. M. Basile, G. Trefoloni, P. Vanni, S. Spolveri, M. C. Baruffi, G. Landini, A. Ghetti, et al.
Characteristics, Outcome, and Care of Stroke Associated With Atrial Fibrillation in Europe : Data From a Multicenter Multinational Hospital-Based Registry (The European Community Stroke Project)
Stroke, February 1, 2001; 32(2): 392 - 398.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
M. A. Kalafut, R. Gandhi, C. S. Kidwell, and J. L. Saver
Safety and Cost of Low-Molecular-Weight Heparin as Bridging Anticoagulant Therapy in Subacute Cerebral Ischemia
Stroke, November 1, 2000; 31(11): 2563 - 2568.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
L. Claesson, G. Gosman-Hedstrom, M. Johannesson, B. Fagerberg, and C. Blomstrand
Resource Utilization and Costs of Stroke Unit Care Integrated in a Care Continuum: A 1-Year Controlled, Prospective, Randomized Study in Elderly Patients : The Goteborg 70+ Stroke Study
Stroke, November 1, 2000; 31(11): 2569 - 2577.
[Abstract] [Full Text] [PDF]


Home page
NeurologyHome page
T. Rundek, H. Mast, A. Hartmann, B. Boden-Albala, L. Lennihan, I.-F. Lin, M. C. Paik, and R. L. Sacco
Predictors of resource use after acute hospitalization: The Northern Manhattan Stroke Study
Neurology, October 24, 2000; 55(8): 1180 - 1187.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
D. Sulch, I. Perez, A. Melbourn, and L. Kalra
Randomized Controlled Trial of Integrated (Managed) Care Pathway for Stroke Rehabilitation
Stroke, August 1, 2000; 31(8): 1929 - 1934.
[Abstract] [Full Text] [PDF]


Home page
StrokeHome page
J. J. Caro, K. F. Huybrechts, and I. Duchesne
Management Patterns and Costs of Acute Ischemic Stroke : An International Study
Stroke, March 1, 2000; 31(3): 582 - 590.
[Abstract] [Full Text] [PDF]