This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by de Koning, I. Articles by Koudstaal, P. J. Search for Related Content PubMed PubMed Citation Articles by de Koning, I. Articles by Koudstaal, P. J. Pubmed/NCBI databases Medline Plus Health Information Stroke Related Collections Behavioral/psychosocial - stroke Other diagnostic testing Behavioral Changes and Stroke

(Stroke. 2000;31:1502.)
© 2000 American Heart Association, Inc.

Original Contributions

A Short Screening Instrument for Poststroke Dementia

The R-CAMCOG

Inge de Koning, MA; Diederik W.J. Dippel, MD, PhD; Fop van Kooten, MD Peter J. Koudstaal, MD, PhD

From the Department of Neurology, University Hospital Rotterdam-Dijkzigt, Rotterdam, the Netherlands.

Correspondence to I. de Koning, Department of Neurology, University Hospital Rotterdam-Dijkzigt, dr. Molewaterplein 40, 3015 GD Rotterdam, Netherlands. E-mail dekoning{at}neur.azr.nl

Background and Purpose—The CAMCOG is a feasible cognitive screening instrument for dementia in patients with a recent stroke. A major disadvantage of the CAMCOG, however, is its lengthy and relatively complex administration for screening purposes. We therefore developed the Rotterdam CAMCOG (R-CAMCOG), based on the original version. Our aim was to reduce the estimated administration time to 15 minutes or less and to retain or perhaps even improve its diagnostic accuracy.

Methods—We analyzed the item scores on the CAMCOG of 300 consecutive stroke patients, after exclusion of patients with a severe aphasia or lowered consciousness level, who were entered in the Rotterdam Stroke Databank. The diagnosis of dementia was made independent of the R-CAMCOG score, on the basis of clinical examination and neuropsychological test results. The R-CAMCOG was constructed in 3 steps. First, items with floor and ceiling effects were removed. Next, subscales with no additional diagnostic value were excluded. Finally, we removed items that did not contribute to the homogeneity of the subscales. The diagnostic accuracy of the R-CAMCOG and the original CAMCOG was determined by means of the area under the receiver operating characteristic (ROC) curve.

Results—In the 3 steps, the number of items was reduced from 59 to 25, divided over the subscales orientation, memory (recent, remote, and learning), perception, and abstraction. The subscale orientation did not reach significance in a logistic regression model but was included in the R-CAMCOG because of its high face validity in dementia screening. Internal validation with ROC analysis suggests that the R-CAMCOG and the CAMCOG are equally accurate in screening for poststroke dementia (area under the curve was 0.95 for both tests).

Conclusions—The R-CAMCOG has overcome the disadvantages of the original CAMCOG. It is a promising, short, and easy-to-administer screening instrument for poststroke dementia. It seems to be sufficiently accurate for this purpose, but the test has yet to be validated in a separate, independent study.

Key Words: dementia • dementia, vascular • stroke

This article has been cited by other articles:

				B. Cullen, B. O'Neill, J. J Evans, R. F Coen, and B. A Lawlor A review of screening tests for cognitive impairment J. Neurol. Neurosurg. Psychiatry, August 1, 2007; 78(8): 790 - 799. [Abstract] [Full Text] [PDF]

				I de Koning, F van Kooten, P J Koudstaal, and D W J Dippel Diagnostic value of the Rotterdam-CAMCOG in post-stroke dementia J. Neurol. Neurosurg. Psychiatry, February 1, 2005; 76(2): 263 - 265. [Abstract] [Full Text] [PDF]