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Stroke. 2001;32:1621-1626

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Medline Plus Health Information
*Aphasia
*Stroke

(Stroke. 2001;32:1621.)
© 2001 American Heart Association, Inc.


Original Contribution

Constraint-Induced Therapy of Chronic Aphasia After Stroke

Friedemann Pulvermüller, PhD; Bettina Neininger, MA; Thomas Elbert, PhD; Bettina Mohr, PhD; Brigitte Rockstroh, PhD; Peter Koebbel, MA Edward Taub, PhD

From the MRC Cognition and Brain Sciences Unit (F.P.), Cambridge, UK; Department of Psychology (F.P., B.G., T.E. B.M., B.R.), University of Konstanz, Konstanz; Lurija Institute of Rehabilitation Research (F.P., B.G.); Neurological Hospital Schmieder (P.K.), Allensbach, Germany; and the Department of Psychology (E.T.), University of Alabama at Birmingham, Birmingham, Ala.

Correspondence and reprint requests to Friedemann Pulvermüller, Cognition and Brain Sciences Unit, Medical Research Council, 15 Chaucer Rd, Cambridge CB2 2EF, UK.

Abstract—Patients with chronic aphasia were assigned randomly to a group to receive either conventional aphasia therapy or constraint-induced (CI) aphasia therapy, a new therapeutic technique requiring intense practice over a relatively short period of consecutive days. CI aphasia therapy is realized in a communicative therapeutic environment constraining patients to practice systematically speech acts with which they have difficulty. Patients in both groups received the same amount of treatment (30 to 35 hours) as 10 days of massed-practice language exercises for the CI aphasia therapy group (3 hours per day minimum; 10 patients) or over a longer period of {approx}4 weeks for the conventional therapy group (7 patients). CI aphasia therapy led to significant and pronounced improvements on several standard clinical tests, on self-ratings, and on blinded-observer ratings of the patients’ communicative effectiveness in everyday life. Patients who received the control intervention failed to achieve comparable improvements. Data suggest that the language skills of patients with chronic aphasia can be improved in a short period by use of an appropriate massed-practice technique that focuses on the patients’ communicative needs.


Key Words: aphasia • physical therapy • speech therapy • treatment outcome




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