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(Stroke. 2002;33:941.)
© 2002 American Heart Association, Inc.

Original Contributions

Dissecting Aneurysms of Intracranial Carotid Circulation

Hiroki Ohkuma, MD; Shigeharu Suzuki, MD Kazumi Ogane, MD for the Study Group of the Association of Cerebrovascular Disease in Tohoku, Japan

From the Department of Neurosurgery, Hirosaki University School of Medicine, Hirosaki, Japan.

Correspondence to Hiroki Ohkuma, MD, Department of Neurosurgery, Hirosaki University School of Medicine, 5 Zaifu-Cho, Hirosaki, 036-8216 Japan. E-mail ohkuma{at}cc.hirosaki-u.ac.jp

Background and Purpose— Clinical features of nontraumatic dissecting aneurysms of intracranial carotid circulation remain unclear because investigation of this disease has been limited to case reports. The aim of this study was to investigate the clinical features of this disease through the use of cooperatively collected cases.

Methods— The cases diagnosed as dissecting aneurysms of intracranial carotid circulation on the basis of clinical signs and neuroradiological findings in 46 stroke centers from 1995 through 1999 were collected, and their clinical features were analyzed.

Results— Forty-nine cases of dissecting aneurysms of intracranial carotid circulation were collected. Thirty-two patients presented with subarachnoid hemorrhage (SAH), and 17 presented with cerebral ischemia. The ratio of this disease to all intracranial dissecting aneurysms treated in the same institutes for the same period was 19.1%, and the ratio of SAH resulting from this disease to SAH of unverified origin treated in the same institutes for the same period was 6.2%. The predominant site of lesion was the internal carotid artery in 18 of 32 patients (56%) with SAH and the anterior cerebral artery in 13 of 17 patients (76%) with cerebral ischemia. The predominant angiographic findings were that stenosis with dilatation occurred in 20 of 32 patients (63%) with SAH and stenosis without dilatation was seen in 11 of 17 patients (65%) with cerebral ischemia. Poor prognosis was seen in 21 of 32 patients (66%) with SAH, which was due largely to rebleeding seen preoperatively, during operation, and even postoperatively when clipping or wrapping of the aneurysmal bulge was performed.

Conclusions— Nontraumatic dissecting aneurysm of intracranial carotid circulation is not as rare as expected. It seems to be one of the important causes of SAH of unverified origin.

Key Words: aneurysm • cerebral aneurysm • cerebral ischemia • dissection • subarachnoid hemorrhage

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