This Article Full Text Full Text (PDF) All Versions of this Article: 35/11/2523    most recent 01.STR.0000144683.96048.98v1 Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Tsiskaridze, A. Articles by Bogousslavsky, J. Search for Related Content PubMed PubMed Citation Articles by Tsiskaridze, A. Articles by Bogousslavsky, J. Related Collections Epidemiology

(Stroke. 2004;35:2523.)
© 2004 American Heart Association, Inc.

Original Contributions

Stroke Incidence and 30-Day Case-Fatality in a Suburb of Tbilisi

Results of the First Prospective Population-Based Study in Georgia

Alexander Tsiskaridze, MD; Mamuka Djibuti, MD; Guy van Melle, PhD; Giorgi Lomidze, MD; Sophia Apridonidze, MD; Iana Gauarashvili, MD; Bartomiej Piechowski-Jówiak, MD; Roman Shakarishvili, MD Julien Bogousslavsky, MD

From the Department of Neurology (A.T., B.P.-J., J.B.), CHUV, Lausanne, Switzerland; the Sarajishvili Institute of Neurology and Neurosurgery (A.T., G.L., S.A., I.G., R.S.), Tbilisi, Georgia; the Department of Public Health and Epidemiology (M.D.), Georgian State Medical Academy Tbilisi, Georgia; and the University Institute of Social and Preventive Medicine (G.v.M.), Lausanne, Switzerland.

Correspondence to Prof Julien Bogousslavsky, Department of Neurology, CHUV, CH-1011, Lausanne, Switzerland. E-mail Julien.Bogousslavsky{at}chuv.hospvd.ch

Background and Purpose— Although stroke is one of the main public health problems worldwide, no study of stroke incidence has been performed in Georgia, and therefore, a population-based registry was established to determine the incidence and case-fatality rates of first-ever stroke.

Methods— We identified all first-ever strokes between November 2000 and July 2003 in a defined population of 51 246 residents in the Sanzona suburb of Tbilisi, the capital of Georgia, using overlapping sources of information and standard diagnostic criteria.

Results— A total of 233 first-ever strokes occurred during the study period. The crude annual incidence rate was 165 (95% CI, 145 to 188) per 100 000 residents. The corresponding rate adjusted to the standard "world" population was 103 (95% CI, 89 to 117). In terms of stroke subtype, the crude annual incidence rate per 100 000 inhabitants was 89 (95% CI, 74 to 106) for ischemic stroke, 44 (95% CI, 34 to 57) for intracerebral hemorrhage, 16 (95% CI, 10 to 25) for subarachnoidal hemorrhage, and 16 (95% CI, 10 to 25) for unspecified stroke, and the corresponding case-fatality rates at 1 month were 19.2%, 48.4%, 47.8%, and 69.6%.

Conclusion— The overall stroke incidence rate in an urban population of Georgia is comparable to those reported in developed countries. As for the stroke subtypes, there is an excess of hemorrhagic strokes compared with other registries. Geographical and lifestyle variations may explain these findings, whereas inadequacy of the stroke care system in Georgia might contribute to the high case-fatality.

Key Words: epidemiology • incidence • stroke

This article has been cited by other articles:

				N K de Rooij, F H H Linn, J A van der Plas, A Algra, and G J E Rinkel Incidence of subarachnoid haemorrhage: a systematic review with emphasis on region, age, gender and time trends J. Neurol. Neurosurg. Psychiatry, December 1, 2007; 78(12): 1365 - 1372. [Abstract] [Full Text] [PDF]

				C. Minelli, L. Fu Fen, and D. P. Camara Minelli Stroke Incidence, Prognosis, 30-Day, and 1-Year Case Fatality Rates in Matao, Brazil: A Population-Based Prospective Study Stroke, November 1, 2007; 38(11): 2906 - 2911. [Abstract] [Full Text] [PDF]

				S. K. Das, T. K. Banerjee, A. Biswas, T. Roy, D. K. Raut, C. S. Mukherjee, A. Chaudhuri, A. Hazra, and J. Roy A Prospective Community-Based Study of Stroke in Kolkata, India Stroke, March 1, 2007; 38(3): 906 - 910. [Abstract] [Full Text] [PDF]