This Article Full Text Full Text (PDF) All Versions of this Article: 35/11/2549    most recent 01.STR.0000144684.46826.62v1 Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Harari, D. Articles by Swift, C. Search for Related Content PubMed PubMed Citation Articles by Harari, D. Articles by Swift, C. Pubmed/NCBI databases Medline Plus Health Information Constipation Stroke Related Collections Other Treatment Rehabilitation, Stroke

(Stroke. 2004;35:2549.)
© 2004 American Heart Association, Inc.

Original Contributions

Treatment of Constipation and Fecal Incontinence in Stroke Patients

Randomized Controlled Trial

From the Department of Aging and Health (D.H., L.L.), Guys and St Thomas’ Hospital, London, UK; the Department of Healthcare of the Elderly (D.H., C.S.), Kings College, London, UK; and the St. Marks Hospital and Florence Nightingale School of Nursing and Midwifery (C.N.), Kings College, London, UK.

Correspondence to Dr Danielle Harari, Consultant Physician/Senior Lecturer, Department of Aging and Health, St. Thomas’ Hospital, 9th Floor, North Wing, Lambeth Palace Rd, London SE1 7EH. E-mail danielle.harari{at}kcl.ac.uk

Background and Purpose— Despite its high prevalence in stroke survivors, there is little clinical research on bowel dysfunction in this population. This is the first randomized controlled trial to evaluate treatment of constipation and fecal incontinence in stroke survivors.

Methods— Stroke patients with constipation or fecal incontinence were identified by screening questionnaire (122 community, 24 stroke rehabilitation inpatients) and randomized to intervention or routine care (73 per group). The intervention consisted of a 1-off structured nurse assessment (history and rectal examination), leading to targeted patient/carer education with booklet and provision of diagnostic summary and treatment recommendations (after consultation with geriatrician) to patient’s general practitioner (GP)±ward physician.

Results— Percentage of bowel movements (BMs) per week graded as "normal" by participants in a prospective 1-week stool diary was significantly higher in intervention versus control patients at 6 months (72% versus 55%; P=0.027), as was mean number of BMs per week (5.2 versus 3.6; P=0.005). There was no significant reduction in fecal incontinence, although numbers were small. At 12 months, intervention patients were more likely to be modifying their diets (odds ratio [OR], 3.1 [1.2 to 8.0]) and fluid intake (OR, 4.2 [1.4 to 12.2]) to control their bowels and to have visited their GP for their bowel problem (OR, 5.0 [1.4 to 17.5]). GP prescribing of laxatives and suppositories was significantly influenced at 12 months.

Conclusions— A single clinical/educational nurse intervention in stroke patients effectively improved symptoms of bowel dysfunction up to 6 months later, changed bowel-modifying lifestyle behaviors up to 12 months later, and influenced patient–GP interaction and physician prescribing patterns.

Key Words: constipation • fecal incontinence • randomized controlled trial • stroke

This article has been cited by other articles:

				H. P. Adams Jr, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, et al. Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Circulation, May 22, 2007; 115(20): e478 - e534. [Abstract] [Full Text] [PDF]

				H. P. Adams Jr, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, et al. Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/ American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists Stroke, May 1, 2007; 38(5): 1655 - 1711. [Abstract] [Full Text] [PDF]

				S M Leary, C Liu, A L Cheesman, A Ritter, S Thompson, and R Greenwood Incontinence after brain injury: prevalence, outcome and multidisciplinary management on a neurological rehabilitation unit Clinical Rehabilitation, December 1, 2006; 20(12): 1094 - 1099. [Abstract] [PDF]

				J. Redfern, C. McKevitt, and C. D.A. Wolfe Development of Complex Interventions in Stroke Care: A Systematic Review Stroke, September 1, 2006; 37(9): 2410 - 2419. [Abstract] [Full Text] [PDF]