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Articles

Risk Factors for Vascular Dementia and Alzheimer Disease

From the Department of Neurology and Rehabilitation, University of Illinois College of Medicine at Chicago, Ill.

Correspondence to Dr Philip B. Gorelick, Department of Neurology and Rehabilitation, University of Illinois College of Medicine at Chicago, 912 South Wood St, Room 855N, Chicago, IL 60612. Email pgorelic{at}uic.edu

Alzheimer disease and vascular cognitive impairment are important causes of cognitive decline in the elderly. It has now been shown that vascular risk factors have measurable negative effects on the brain and are associated with cognitive impairment. We review vascular factors that might be responsible to cognitive decline in Alzheimer disease and vascular cognitive impairment and the corresponding intervenvations that might prevent cognitive impairment as we age.

Key Words: Alzheimer disease • cognitive disorders • risk factors

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