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(Stroke. 2004;35:2691.)
© 2004 American Heart Association, Inc.

Articles

Recovery and Rehabilitation in Stroke

Stem Cells

From the Laboratory of Neurogenesis and Cell Therapy, Wallenberg Neuroscience Center (O.L.), and the Laboratory of Neural Stem Cell Biology, Stem Cell Institute (Z.K.), University Hospital, Lund, Sweden; and the Lund Strategic Research Center for Stem Cell Biology and Cell Therapy (O.L., Z.K.), Lund, Sweden.

Correspondence to Dr Olle Lindvall, Section of Restorative Neurology, Wallenberg Neuroscience Center, University Hospital BMC A-11, SE-221 84 Lund, Sweden. E-mail olle.lindvall{at}neurol.lu.se

The recent demostration that neurons for transplantation can be generated from stem cells and that the adult brain produces new neurons in response to stroke has raised hope for the development of a stem cell therapy for patients affected with this disorder. In this review we propose a road map to the clinic and describe the different scientific tasks that need to be accomplished to move stem cell–based approaches toward application in stroke patients.

Key Words: acute care • rehabilitation • stem cells • stem cell transplantation