Published online before print June 10, 2004, doi: 10.1161/01.STR.0000134416.89389.9d
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
(Stroke. 2004;35:1842.)
© 2004 American Heart Association, Inc.
Original Contributions |
Stroke Risk After Transient Ischemic Attack in a Population-Based Setting
From the Stroke Program (L.D.L., D.L.B., M.A.S., N.M.G., L.B.M.), University of Michigan Medical School, Ann Arbor, Mich.; the Stroke Program (J.K.I.), University of Texas Medical School at Houston; the Department of Epidemiology (J.M.H.R.), University of Texas School of Public Health at Houston; and the Department of Epidemiology (L.B.M.), University of Michigan School of Public Health, Ann Arbor, Mich.
Correspondence to Dr Lewis B. Morgenstern, Stroke Program, University of Michigan Medical School, 1500 East Medical Center Drive, TC 1920/0316, Ann Arbor, MI 48109-0316. E-mail LMorgens{at}umich.edu
Background and Purpose— Stroke risk after transient ischemic attack (TIA) has not been examined in an ethnically diverse population-based community setting. The purpose of this study was to identify stroke risk among TIA patients in a population-based cerebrovascular disease surveillance project.
Methods— The Brain Attack Surveillance in Corpus Christi (BASIC) Project prospectively ascertains stroke and TIA cases in a geographically isolated Southeast Texas County. The community is approximately half Mexican American and half nonHispanic white. Cases are validated by board-certified neurologists using source documentation. Cumulative risk for stroke after TIA was determined using Kaplan-Meier estimates. Cox proportional hazards regression was used to test for associations between stroke risk after TIA and demographics, symptoms, risk factors, and history of stroke/TIA.
Results— BASIC identified 612 TIA cases between January 1, 2000, and December 31, 2002; 60.9% were female and 48.0% were Mexican American. Median age was 73.8 years. Stroke risk within 2 days, 7 days, 30 days, 90 days, and 12 months was 1.64%, 1.97%, 3.15%, 4.03%, and 7.27%, respectively. Stroke risk was not influenced by ethnicity, symptoms, or risk factors.
Conclusions— Using a population-based design, we found that early stroke risk after TIA was less than previously reported in this bi-ethnic population of Mexican Americans and nonHispanic whites. Approximately half of the 90-day stroke risk after TIA occurred within 2 days.
Key Words: cerebral ischemia, transient • stroke • population surveillance • Hispanic Americans • Mexican Americans • risk • mortality
This article has been cited by other articles:
 |
|
 |
|
  A. Chandratheva, Z. Mehta, O. C. Geraghty, L. Marquardt, P. M. Rothwell, and On behalf of the Oxford Vascular Study Population-based study of risk and predictors of stroke in the first few hours after a TIA Neurology, June 2, 2009; 72(22): 1941 - 1947. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. H. Lichtman, S. B. Jones, E. Watanabe, N. B. Allen, Y. Wang, V. J. Howard, and L. B. Goldstein Elderly Women Have Lower Rates of Stroke, Cardiovascular Events, and Mortality After Hospitalization for Transient Ischemic Attack Stroke, June 1, 2009; 40(6): 2116 - 2122. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Easton, J. L. Saver, G. W. Albers, M. J. Alberts, S. Chaturvedi, E. Feldmann, T. S. Hatsukami, R. T. Higashida, S. C. Johnston, C. S. Kidwell, et al. Definition and Evaluation of Transient Ischemic Attack: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease: The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke, June 1, 2009; 40(6): 2276 - 2293. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 WRITING GROUP MEMBERS, D. Lloyd-Jones, R. Adams, M. Carnethon, G. De Simone, T. B. Ferguson, K. Flegal, E. Ford, K. Furie, A. Go, et al. Heart Disease and Stroke Statistics--2009 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Circulation, January 27, 2009; 119(3): e21 - e181. [Full Text] [PDF]
|
|
|
|
|
|
Writing Group Members, W. Rosamond, K. Flegal, K. Furie, A. Go, K. Greenlund, N. Haase, S. M. Hailpern, M. Ho, V. Howard, et al. Heart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Circulation, January 29, 2008; 117(4): e25 - e146. [Full Text] [PDF]
|
|
|
|
 |
|
 J R Selvarajah, C J Smith, S Hulme, R F Georgiou, A Vail, P J Tyrrell, and on behalf of the NORTHSTAR Collaborators Prognosis in patients with transient ischaemic attack (TIA) and minor stroke attending TIA services in the North West of England: The NORTHSTAR Study J. Neurol. Neurosurg. Psychiatry, January 1, 2008; 79(1): 38 - 43. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. M. Wu, K. McLaughlin, D. L. Lorenzetti, M. D. Hill, B. J. Manns, and W. A. Ghali Early Risk of Stroke After Transient Ischemic Attack: A Systematic Review and Meta-analysis Arch Intern Med, December 10, 2007; 167(22): 2417 - 2422. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. A. Nickman, J. Biskupiak, F. Creekmore, H. Shah, and D. I . Brixner Antiplatelet medication management in patients hospitalized with ischemic stroke Am. J. Health Syst. Pharm., November 1, 2007; 64(21): 2250 - 2256. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Rosamond, K. Flegal, G. Friday, K. Furie, A. Go, K. Greenlund, N. Haase, M. Ho, V. Howard, B. Kissela, et al. Heart Disease and Stroke Statistics--2007 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Circulation, February 6, 2007; 115(5): e69 - e171. [Full Text] [PDF]
|
|
|
|
|
|
T. Thom, N. Haase, W. Rosamond, V. J. Howard, J. Rumsfeld, T. Manolio, Z.-J. Zheng, K. Flegal, C. O'Donnell, S. Kittner, et al. Heart Disease and Stroke Statistics--2006 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Circulation, February 14, 2006; 113(6): e85 - e151. [Full Text] [PDF]
|
|
|
|
|
|
D. Kleindorfer, P. Panagos, A. Pancioli, J. Khoury, B. Kissela, D. Woo, A. Schneider, K. Alwell, E. Jauch, R. Miller, et al. Incidence and Short-Term Prognosis of Transient Ischemic Attack in a Population-Based Study Stroke, April 1, 2005; 36(4): 720 - 723. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. B. Goldstein and P. Amarenco Prevention and Health Services Delivery Stroke, February 1, 2005; 36(2): 222 - 224. [Full Text] [PDF]
|
|
|
|
|
|
M.A. Whitehead, J. McManus, C. McAlpine, P. Langhorne, L. D. Lisabeth, and L. B. Morgenstern Early Recurrence of Cerebrovascular Events After Transient Ischaemic Attack Stroke, January 1, 2005; 36(1): 1 - 1. [Full Text] [PDF]
|
|