Published online before print July 1, 2004, doi: 10.1161/01.STR.0000135763.62131.6a
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(Stroke. 2004;35:2134.)
© 2004 American Heart Association, Inc.
Original Contributions |
Pro-CAS
A Prospective Registry of Carotid Angioplasty and Stenting
From the Medizinische Klinik der Technischen Universität (W.T.), Munich, Germany; the Bayerische Arbeitsgemeinschaft für Qualitätssicherung in der Stationären Versorgung (P.H.), Munich, Germany; the Institut für Strahlendiagnostik der Städtischen Kliniken (K.M.), Dortmund, Germany; the Abteilung Angiologie der Universität (R.A.), Vienna, Austria; the Institut für Radiologie des Knappschaftskrankenhaus (L.H.), Bochum, Germany; the Abteilung für Interventionelle Radiologie des Krankenhaus Neunkirchen (F.-J.H.), Neunkirchen, Germany; the Abteilung Innere Medizin und Interventionelle Angiologie des Marienhospital (R.K.), Kevelaer, Germany; the Medizinische Abteilung des AÖ Krankenhaus (F.L.), Linz, Austria; the Cardiovascular Center (H.S.), Frankfurt, Germany; and the Klinik für Operative und Interventionelle Gefäßchirurgie (S.v.S.), Behandlungszentrum Vogtareuth, Germany.
Correspondence to Prof Dr Wolfram Theiss, 1 Medizinische Klinik der TUM, Ismaninger Str 22, D-81675 München, Germany. E-mail theiss{at}med1.med.tu-muenchen.de
Background and Purpose— The German Societies of Angiology and Radiology have instituted a prospective registry of carotid angioplasty and stenting (CAS) to limit uncontrolled use of CAS and to collect data about technique and results of CAS outside clinical trials.
Methods— A total of 38 centers register their patients prospectively before CAS is performed. At discharge, technical details, periprocedural medication, and the clinical course are reported on a standardized form.
Results— During the first 48 months, 3853 planned interventions were recorded, and CAS was actually attempted on 3267 patients of whom 1827 (56%) were symptomatic and 1433 (44%) were asymptomatic. In 3127 (98%) cases, stents were used, of which 2784 (89%) were of the self-expanding type. Other technical aspects such as the use of guiding catheters and protection devices varied widely among the centers. Periprocedural medication rather uniformly included aspirin and clopidogrel before and after CAS and high-dose heparin and atropin during CAS. CAS was successful in 3207 (98%) cases. There was a 0.6% (n=18) mortality rate, a 1.2% (n=38) major stroke rate, and a 1.3% (n=41) minor stroke rate. The combined stroke and death rate was 2.8% (n=90).
Conclusions— These prospective multicenter data are likely to give a realistic picture of the possibilities and limitations of CAS in the general community. They suggest that CAS may be performed with similar results in the general community as they have been reported by highly specialized centers and in clinical studies.
Key Words: angioplasty • carotid stenosis • primary prevention • secondary prevention • stents • stroke
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