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(Stroke. 2005;36:2094.)
© 2005 American Heart Association, Inc.

Original Contributions

Prevalence of Carotid Artery Stenosis in Patients With Coronary Artery Disease in Japanese Population

Shuzou Tanimoto, MD; Yuji Ikari, MD, PhD; Kengo Tanabe, MD, PhD; Sen Yachi, MD; Hiroyoshi Nakajima, MD, PhD; Tomohiro Nakayama, MD; Mitsuharu Hatori, MD; Gaku Nakazawa, MD; Yoshinobu Onuma, MD; Yasutomi Higashikuni, MD; Hirosada Yamamoto, MD; Eiichi Tooda, RMS Kazuhiro Hara, MD, PhD

From the Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan.

Reprint requests to Shuzou Tanimoto, Department of Interventional Cardiology, Thorax Center, H922, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. E-mail Shuzou_bushido{at}msn.com

Background and Purpose— Prevalence of carotid artery stenosis in patients with coronary artery disease (CAD) is unknown in Japanese population.

Methods— The study populations consisted of 632 consecutive patients who underwent coronary angiography because of suspicion of CAD. All patients underwent carotid ultrasonography to screen carotid artery stenosis before coronary angiography. We defined echographic carotid stenosis as area stenosis of >50% or peak systolic velocity of >200 cm/s.

Results— Echographic carotid stenosis was observed in 124 patients (19.6%). Coronary angiography revealed 433 patients had CAD. Prevalence of echographic carotid artery stenosis was 14 of 199 (7.0%), 18 of 124 (14.5%), 28 of 131 (21.4%), and 64 of 178 (36.0%) in patients with 0-, 1-, 2-, and 3-vessel CAD, respectively (P<0.0001). The prevalence rate with carotid stenosis and CAD was 25.4%. Multivariate stepwise logistic regression analysis showed that age and the extent of CAD were independently related to the presence of carotid stenosis (P=0.0002 and <0.0001, respectively).

Conclusions— Prevalence of carotid stenosis in patients with CAD is high in Japan as well as in Western countries. Screening of carotid artery stenosis is recommended especially in older patients with multivessel CAD.

Key Words: carotid stenosis • coronary artery disease • epidemiology • Japan

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