This Article Full Text Full Text (PDF) All Versions of this Article: 36/7/1507    most recent 01.STR.0000170991.63594.b6v1 Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Bravata, D. M. Articles by Concato, J. Search for Related Content PubMed PubMed Citation Articles by Bravata, D. M. Articles by Concato, J. Pubmed/NCBI databases Substance via MeSH Medline Plus Health Information Stroke Related Collections Acute Cerebral Infarction Acute Stroke Syndromes

(Stroke. 2005;36:1507.)
© 2005 American Heart Association, Inc.

Original Contributions

Racial Disparities in Stroke Risk Factors

The Impact of Socioeconomic Status

Dawn M. Bravata, MD; Carolyn K. Wells, MPH; Barbara Gulanski, MD; Walter N. Kernan, MD; Lawrence M. Brass, MD; Judith Long, MD John Concato, MD

From the Clinical Epidemiology Research Center (CERC; D.M.B., C.K.W., J.C.), Internal Medicine Service (D.M.B., B.G., J.C.), Neurology Service (L.M.B.), Veterans Affairs Connecticut Healthcare System, West Haven, Conn; the Department of Internal Medicine (D.M.B., C.K.W., B.G., W.N.K., J.C.) and Department of Neurology (L.M.B.), Yale University School of Medicine, New Haven, Conn; the Department of Internal Medicine (J.L.), Philadelphia Veterans Affairs Center for Health Equity Research and Promotion and the University of Pennsylvania School of Medicine, Philadelphia, Pa.

Correspondence to Dawn M. Bravata, MD, Clinical Epidemiology Research Center (CERC), VA Connecticut Healthcare System, West Haven VA Medical Center, Building 35A, Mailcode 151B, 950 Campbell Avenue, West Haven, CT 06516. E-mailDawn.Bravata{at}yale.edu

Background and Purpose— In the US, blacks have a higher incidence of stroke and more severe strokes than whites. Our objective was to determine if differences in income, education, and insurance, as well as differences in the prevalence of stroke risk factors, accounted for the association between ethnicity and stroke.

Methods— We used data from the Third National Health and Nutrition Survey (NHANES III), a cross-sectional sample of the noninstitutionalized US population (1988–1994), and included blacks and whites aged 40 years or older with a self-reported stroke history. Income was assessed using a ratio of income to US Census Bureau annual poverty threshold.

Results— Among 11 163 participants, 2752 (25%) were black and 619 (6%) had a stroke history (blacks: 160/2752 [6%]; whites: 459/8411 [6%]; P=0.48). Blacks had a higher prevalence of 5 risk factors independently associated with stroke: hypertension, treated diabetes, claudication, higher C-reactive protein, and inactivity; whites had a higher prevalence of 3 risk factors: older age, myocardial infarction, and lower high-density lipoprotein cholesterol. Ethnicity was independently associated with stroke after adjusting for the 8 risk factors (adjusted odds ratio, 1.32; 95% CI, 1.04 to 1.67). Ethnicity was not independently associated with stroke after adjustment for income and income was independently associated with stroke (adjusted odds ratios for: ethnicity, 1.15; 95% CI, 0.88 to 1.49; income, 0.89; 95% CI, 0.82 to 0.95). Adjustment for neither education nor insurance altered the ethnicity–stroke association.

Conclusions— In this study of community-dwelling stroke survivors, ethnic differences exist in the prevalence of stroke risk factors and income may explain the association between ethnicity and stroke.

Key Words: ischemia • risk factors • social class

This article has been cited by other articles:

				P. U. Heuschmann, A. P. Grieve, A. M. Toschke, A. G. Rudd, and C. D.A. Wolfe Ethnic Group Disparities in 10-Year Trends in Stroke Incidence and Vascular Risk Factors: The South London Stroke Register (SLSR) Stroke, August 1, 2008; 39(8): 2204 - 2210. [Abstract] [Full Text] [PDF]

				P. A. Wolf and W. B. Kannel Preventing Stroke: Does Race/Ethnicity Matter? Circulation, November 6, 2007; 116(19): 2099 - 2100. [Full Text] [PDF]

				H. S. Markus, U. Khan, J. Birns, A. Evans, L. Kalra, A. G. Rudd, C. D.A. Wolfe, and P. Jerrard-Dunne Differences in Stroke Subtypes Between Black and White Patients With Stroke: The South London Ethnicity and Stroke Study Circulation, November 6, 2007; 116(19): 2157 - 2164. [Abstract] [Full Text] [PDF]