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(Stroke. 2006;37:2784.)
© 2006 American Heart Association, Inc.

Original Contributions

Progressive Decline in Stroke Mortality in Brazil From 1980 to 1982, 1990 to 1992, and 2000 to 2002

From Disciplina de Neurologia (C.A.), Faculdade de Medicina, Universidade Federal do Rio de Janeiro; Instituto de Medicina Social (C.C.C., R.V.), Universidade Estadual do Rio de Janeiro; and Departamento de Epidemiologia e Métodos Quantitativos em Saúde (C.B.d.C.), ENSP/FIOCRUZ, Rio de Janeiro, Brazil.

Correspondence to Dr Charles André, Hospital Universitário Clementino Fraga Filho, Serviço de Neurologia, Av Brigadeiro Trompowsky, s/n0, sala 10E36, CEP 21941-590, Rio de Janeiro, Brasil. E-mail andrecmd{at}unisys.com.br

Background and Purpose— We describe the trends in stroke mortality in Brazil during 3 decades and investigate their differences according to regional disparities, sex, and age distributions.

Methods— Official data on mortality and population estimates were retrieved to calculate standardized mortality rates (with the 1980 Brazilian population as a reference) in 6 age strata and in the 5 political regions for the initial period (3 first years) of the 1980, 1990, and 2000 decades. Data were corrected for undefined causes of death. The Poisson model was used to estimate risk reduction during the 3 decades and to study the interaction between those rates and sex, age strata, and regions.

Results— The stroke standardized mortality rate decreased consistently in the last 20 years, from 68.2 to 40.9 per 100 000 habitants. This reduction paralleled a decrease in total cardiovascular mortality rates in the same period, from 208.2 to 126.1 per 100 000 habitants. The reduction in stroke standardized mortality rate was detected in men and women and in all age strata. The reduction was evident in all geopolitical regions of the country, with the wealthiest regions’ exhibiting higher initial rates and more marked standardized mortality rate reductions. The risk of dying of stroke in the period 2000 to 2002 was 0.45 (95% CI, 0.44 to 0.45) of that found in the period 1980 to 1982.

Conclusions— The risk of dying of stroke in Brazil declined dramatically between the initial period in the early 1980s and the early 2000s. The decline was especially marked in the most developed regions and may reflect an improvement in general health conditions during the study period.

Key Words: stroke • epidemiology • mortality • socioeconomic factors

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