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(Stroke. 2007;38:691.)
© 2007 American Heart Association, Inc.

Genomics of Ischemia: Introduction

Genomic Profiles of Stroke in Blood

Frank R. Sharp, MD; Huichun Xu, MD; Lisa Lit, MS; Wynn Walker, PhD; Joseph Pinter, MD; Michelle Apperson, MD Piero Verro, MD

From the Department of Neurology (F.R.S., H.X., L.L., W.W., J.P., M.A., P.V.) and the Medical Investigation of Neurodevelopmental Disease Institute (F.R.S., H.X., L.L., W.W., J.P., M.A.), University of California at Davis, Davis, Calif.

Correspondence to Prof Frank R. Sharp, Department of Neurology and the Medical Investigation of Neurodevelopmental Disease Institute, Neuroscience and Genetics Graduate Programs, University of California at Davis Medical Center, 2805 50th Street, Rm 2416, Sacramento, CA 95817. E-mail frank.sharp{at}ucdmc.ucdavis.edu; frsharp@ucdavis.edu

Abstract

These studies show that gene expression changes in most patients by 2 to 3 hours after ischemic stroke, and in all patients studied by 24 hours.

Key Words: diagnostic methods • gene regulation • genomics • ischemia • immunology • inflammation • pathobiology • pathogenesis • stroke