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(Stroke. 2007;38:2592.)
© 2007 American Heart Association, Inc.

Research Letters

South Asian Patients With Ischemic Stroke

Intracranial Large Arteries Are the Predominant Site of Disease

Deidre A. De Silva, MRCP; Fung-Peng Woon, MSc; Moi-Pin Lee, RBT; Christopher P.L.H. Chen, FRCP; Hui-Meng Chang, MBBS, FAMS Meng-Cheong Wong, MBBS, FRCP

From the National Neuroscience Institute (D.A.D., H.M.C., M.C.W.), Singapore General Hospital Campus, Singapore; the National Heart Centre (F.P.W.), Singapore; Singapore General Hospital (M.P.L.), Singapore; and the National University of Singapore (C.P.L.H.C.), Singapore.

Correspondence to D.A. De Silva, MRCP, Department of Neurology, Singapore General Hospital, Outram Road, Singapore 169608. E-mail gnrdsd{at}sgh.com.sg

Abstract

Background and Purpose— South Asians are the most prevalent ethnic group in the world. Intracranial disease is the most common vascular lesion worldwide.

Methods— We prospectively studied 200 consecutive ethnic South Asian patients with acute ischemic stroke in Singapore.

Results— Intracranial large-artery disease was prevalent among 54% of all stroke subtypes and was independently associated with hypertension and higher serum erythrocyte sedimentation rate.

Conclusions— Among ethnic South Asian patients with ischemic stroke, intracranial large arteries are the predominant site of disease.

Key Words: hypertension • inflammation • intracranial • ischemic stroke • South Asian

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